Fellowship Program Director of the Division of Pediatric Rheumatology, Associate Director of the Medical Scientist Training Program, Director of Pediatric Physician Scientist Training Program, Associa
Research Interests: Understanding the pathogenesis of autoimmune diseases with particular emphasis on immune-mediated cardiovascular disease.
Assistant Professor, Medicine
Research Interests: The Bold lab will focus on using advanced genetic tools in Mycobacterium tuberculosis to understand the targets and mechanisms of protective immunity in tuberculosis, as well as novel methods by which the bacteria evade immune destruction.
Professor and Virginia and David C. Utz Land Grant Chair in Fundamental Immunobiology, Laboratory Medicine and Pathology
Research Interests: How cytokines and cytokine-dependent signal transduction pathways control regulatory T cell development and B cell leukemia
Assistant Professor, Pharmacology
Research Interests: Regulation of membrane-proximal signaling in hematopoietic cells, macrophage response due to inflammation, including the tumor microenvironment in breast cancer; the regulation of proto-oncogenic signaling proteins like the Src family kinases
Associate Professor, Laboratory Medicine and Pathology
Research Interests: Manipulating CD8 T cells to elicit optimal response to pathogen infection, as well as CD8 T cell activation, T cell memory generation and maintenance, enhancing protective immunity, and inhibiting T cell pathology
Associate Director, Center for Immunology; David M. Brown Professor, Laboratory Medicine and Pathology
Research Interests: Molecular mechanisms of T cells in the thymus; gene expression profiling, and RNAi "knock-down" analysis; immune response to the Epstein Barr Virus - a chronic viral infection associated with cancer and autoimmunity in humansLab website
Assistant Professor, Division of Cardiothoracic Surgery
Research Interests: Surgical outcomes in lung transplantation. Use of ex vivo lung perfusion in standard of care as well as expanded criteria lung donors. The tracking and characterization of graft antigen-specific CD4 T cells responses with respect to antibody mediated rejection and chronic lung allograft disease in the lung transplant recipients.
Chairman's Fund Professor in Experimental Pathology, Laboratory Medicine and Pathology
Research Interests: Mechanisms that control development, homeostasis and trafficking of naive and memory CD8 T cells; the regulation of protective immunity versus immunopathology in T cell responses.Lab website
Director, Center for Immunology;Regents and Distinguished McKnight University Professor, Microbiology and Immunology
CD4 helper T and B cell activation by directly tracking Agn-specific cells, with the goal of achieving an understanding of lymphocyte signal transduction, proliferation, and differentiation processes to improve vaccines and prevent autoimmunity
Research Interests: Mechanisms of colon cancer pathogenesis in patients with cystic fibrosis, which has become recognized as a genetic colon cancer syndrome; role of gut microbiota and inflammatory pathways in the colon mucosa
Distinguished McKnight University Professor, Microbiology and Immunology
Research Interests: Resident memory T cells, cytotoxic T cell migration, differentiation and function within tissues, and CD8 T cell vaccines and memory development in response to infectionsLab website
Director of Rheumatic and Autoimmune Diseases; Professor, Medicine
Research Interests: Biological and biochemical nature of immune self-tolerance and application to the treatment of autoimmune diseases, specifically the breakdown of B cell tolerance during disease development. T cell clonal expansion, allograft rejection, and immunotherapy of cancer
Associate Director, UMN Dept. of Medicine Physician Scientist Training Program; Associate Professor, Medicine
Research Interests: The role of adaptor proteins in T cell development, regulation of T cell-dependent autoimmunity, and immune cell transduction
Associate Professor, Department of Pharmacology
Research Interest:The pre-clinical development of novel therapies for drug addiction. Uncovering the mechanisms underlying efficacy of treatment in animal models of prescription opioid abuse and nociception. This is achieved through the implementation of a variety of strategies used to generate more effective vaccines or antibody-based therapies against drugs of abuse, in addition to other unmet medical needs such as antibiotic-resistant bacteria.
Distinguished University Teaching Professor and Harry Kay Chair, Laboratory Medicine and Pathology; Director, Medical Scientist Training Program (MD/PhD); Assistant Dean for Graduate Education
Research Interests: Intracellular signal transduction events that regulate adhesion interactions critical for effective agn-specific immune responses & cell traffickingLab website
Assistant Professor, Medicine
Research Interests: Generating new MHCII tetramer reagents and monoclonal antibodies to understand antigen specific responses in both people and mice with type 1 diabetes and cancer associate autoimmunity.
Associate Professor, Microbiology and Immunology
Research Interests: Investigation of how T cell tolerance to self-antigens, tumor antigens, and proteins from chronic infections is induced and maintained; development of methods for reversing established tolerance to these types of proteins and their translation to the clinicLab website
Assistant Professor, Integrative Biology & Physiology
Research Interests: The Williams lab is working on elucidating mechanisms that regulate the recruitment and differentiation of innate immune cells in atherosclerotic plaque. Cutting edge approaches such as single-cell RNA sequencing and intravital imaging are used to make innovative observations that will expand our understanding of immunity in cardiovascular disease.
Bio Discovery District (BDD) Faculty
U of MN Medical Center (UMMC) Faculty
St. Paul and Off Campus Faculty
Associate Professor, College of Veterinary Medicine