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The Center for Immunology is an interdisciplinary research program at the University of Minnesota devoted to advancing the field of immunology and educating future immunologists.

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CFI is honored to announce that our Director Marc Jenkins, PhD has been elected to the National Academy of Sciences. Marc's achievement is especially notable in that it has been over 50 years since a UMN Medical School faculty member has been added to this impressive organization of the country’s leading researchers. The National Academy of Sciences elects new members in recognition of their distinguished and continuing achievements in original research. Membership is a widely accepted mark of excellence in science and is considered one of the highest honors that a scientist can receive. Current NAS membership totals approximately 2,400 members and 500 foreign associates, of which approximately 190 have received Nobel prizes. Dr. Marc Jenkins has led a distinguished career whose scientific endeavors have answered critical questions in the field of immunology…. Marc is an exemplary scientist, educator, mentor, and advisor. To read more about Marc's accomplishments please click here. We are planning a virtual celebration to honor Dr. Jenkins. Please watch for more details on how to join our celebration, dates and time of the celebration will be listed here and on our Twitter account, @CFI_UMN.

 

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As a result of the increased use of Zoom meetings globally, they have become a target for meeting hijackers. Read about how to Secure Your Zoom Meeting before it occurs, while you are meeting, and after it is over. You can also watch a short demonstration of In-Meeting Tools to Secure your Zoom Meetings.

 

Congratulations!!

Dr. Harry Orr earned the 2020 Carole J. Bland Outstanding Faculty Mentor Award. The award honors faculty who serve as role models for each other, promote the professional development of others and creates a supportive, positive working environment.  Bland was a long-time faculty member in the Department of Family Medicine and Community Health.  The full announcement is here.

Drs. Xavier Revelo and Haiguang Wang have been awarded an American Association of Immunologists 2020 Careers in Immunology Fellowship. The AAI Careers in Immunology Fellowship Program supports the career development of young scientists by providing eligible PIs with one year of salary support for a trainee in their lab.  Postdoctoral trainee, Dr. Wang will receive salary support for his work in the Revelo lab beginning in August. Congratulations to both Drs. Revelo and Wang. For more information on the work being done in Dr. Revelo's lab click here.  We would also like to welcome Haiguang back to Minnesota! He originally trained in Kris Hogquist's lab before doing his first post doc in Dario Vignali's lab at the University of Pittsburgh, PA.

CFI would like to Congratulate Dr. David Masopust and Dr. Ryan Langlois on their recent awards and honors.  Dr. David Masopust, was named as one of the 2020 Distinguished McKnight University Professors. The Distinguished McKnight University Professorship program recognizes outstanding mid-career faculty members who have recently achieved full professor status, especially those who have made significant advances in their careers at the University of Minnesota, whose work and reputation are identified with the University, and whose accomplishments have brought renown and prestige to Minnesota and to their scholarly fields. Dr. Ryan Langlois has been named a 2020 McKnight Presidential Fellow. The McKnight Presidential Fellows Program is a three-year award given to exceptional faculty who have just achieved tenure and promotion to associate professor, to recognize their accomplishments and support their ongoing research and scholarship.  It recognizes recipients who are recommended by their college dean and chosen at the discretion of the executive vice president and provost based on excellence in research and scholarship, leadership, potential to build top-tier programs, and ability to advance University of Minnesota priorities.

Ben Brian is the winner of 2 Medical school awards, he won the 2020 the Veneziale-Steer Award, which recognizes outstanding basic scientific research by a graduate student or a medical student in the field of cellular growth regulation.  Ben also was one of the recipients of the  2020 J. Jacob Kaplan award for his work in immunology in diagnosis and treatment of cancer .  This award is presented annually for the most meritorious student papers on either clinical or basic medical research. The awards are intended to encourage and recognize scholarly achievement in medical research by young investigators at the University of Minnesota Medical School. Ben is a Pharmacology Graduate Student in the lab of Tanya Freedman

Congratulations to Dr. Peter Krueger, a postdoctoral researcher in Dr. Marc Jenkins lab and Dr. April Huseby Kelcher, a postdoctoral researcher in Dr. Marco Pravetoni's lab.  Peter and April have been named to the tenth class of Public Policy Fellows of the American Association of Immunologists!   The program engages postdoctoral fellows in public policy and legislative activities of AAI that impact biomedical research. Congratulations to both of you!!

Dr. Rachel Johnson earned the 2020 UMN Morris Alumni Association Teaching Award! The University of Minnesota, Morris Alumni Association established the UMMAA Teaching Award to honor individual faculty members for outstanding contributions to undergraduate education. Johnson, an Immunologist, stands out among peers for her commitment to undergraduate teaching and learning.

CFI would also like to recognize and congratulate our colleague and former @CFI_UMN member Lalit Beura, Assistant Professor of Molecular Microbiology and Immunology @BrownUniversity. He was chosen to be a 2020 Searle Scholar for his adaptation of resident memory CD8 T lymphocytes in the reproductive mucosa.  The Searle Scholar program is a career development award made annually to 15 US faculty in the first or second year of their first tenure-track assistant professor position in biomedical research, medicine, chemistry, and the biological sciences. The award recognizes faculty who are considered most promising and have made "important, innovative research" contributions and who have the potential for making continuing significant contributions.

Congratulations to all the recipients!! 

 

AAI bestows their highest honor the Lifetime Achievement Award to Dr. Marc Jenkins

The American Association of Immunologists (AAI) has bestowed their highest honor on Dr. Marc Jenkins.  The 2020 Lifetime Achievement Award recognizes a deserving AAI member for a career of scientific achievement and for contributions to AAI and fellow immunologists and to the field of immunology.   For more information on all of Dr. Jenkins's achievements go here.  CFI would like to extend our congratulations and thank Dr. Jenkins for his guidance and leadership as well as the inspiration he inspires as a teacher, mentor, and scientist to those not only at our University but worldwide.

 

The Center for Immunology proudly hosted its first-ever Alumni Celebration

ThanksOn Thursday, April 18, 2019, the Center for Immunology hosted its first Alumni Celebration. The event welcomed over 100 current faculty and students, alumni, professors and more. We were especially happy to welcome Drs. David Brown, Gus Dalmasso, Paul Quie and John Crosson who made special trips to campus just for the occasion of the reunion. At the event, the Robert A. Good Door was presented (see photos) and will be hung at the Center for Immunology.  Drs. Marc Jenkins and Matt Mescher also announced the creation of a new fund to enhance the student experience within the Center. The Mescher Trainee Enhancement fund, an endowed fund, will live in perpetuity at the University of Minnesota and will be available to the Center for Immunology's students. The fund will help with costs like conference registration and travel, equipment and technology, emergency needs and other expenses which can make all the difference in training the next generation of scientists.  To date, $60,000 has been raised with a goal of $100,000. If you were interested in making a gift, and have not done so yet - or were unable to attend the event but still want to support the CFI while honoring Dr. Mescher -visit the fund here. You may also contact Sarah Barsness at the University of Minnesota Foundation if you'd like to make a gift using your IRA, estate plans, donor-advised fund, or other means of charitable giving. Sarah's contact information is 612-625-5976 or sbarsnes@umn.edu. Please click here to see all the great pictures taken
at the event!
 

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  • Naive B Cells with High-Avidity Germline-EncodedAntigen Receptors Produce Persistent IgM+andTransient IgG+Memory B Cells

    Immune memory often lasts for life, this is not the case for certain vaccines in some individuals. By studying B cell responses to phycoerythrin, in the June 2018 issue of Immunity, Pape et al. find that memory B cell responses can be shortlived when generated from precursors that experience unusually strong early signals of avid antigen binding via germline-encoded VH elements. Read more

  • Beura, Et Al, Nature Immunology paper 19,173-182 (2018)

    Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory

    Using two-photon intravital microscopy to visualize the responses of CD8resident memory T cells (Trm cells), Post Doctoral fellows in Masopust, Vezys, and Fife labs found that the Trm cells were highly motile but would pause and undergo in situ division after antigen challenge. Read more

  • Co-housing with pet store mice changes the immune system of laboratory mice

     Nature  highlights the work of Lalit Beura, Sara Hamilton, Marc Jenkins, Vaiva Vezys, Steve Jameson, Dave Masopust, et.al. and their evidence of how laboratory rodents can skew immunology research but that "dirty mice" can clean up the results. Read more

  • Thymic regulatory T cells arise via two distinct developmental programs

    The developmental programs that generate a broad repertoire of regulatory T cells (Treg cells) able to respond to both self-antigens and non-self antigens remain unclear. Here the Farrar lab et al. found that mature Treg cells were generated through two distinct developmental programs involving CD25+ Treg cell progenitors and Foxp3lo Treg cell progenitors (Foxp3lo TregP cells). Read more 

  • Chrysalis: A New Method for High-Throughput Histo-Cytometry Analysis of Images and Movies

    Advances in imaging have led to the development of powerful multispectral, quantitative imaging techniques, like histo-cytometry. The utility of this approach is limited, however, by the need for time-consuming manual image analysis. In an effort to address the time issue, Kotov and Pengo et al. created the software Chrysalis along with a suite of Imaris Xtensions to batch image processing and analysis to automate the processing workflow for confocal, epi-fluorescence, and two-photon microscopy images. Read more

     

  • Dual TCR T Cells: Identity Crisis or Multitaskers?

    In this study, Drs. Binstadt and Schuldt aim to provide a brief but comprehensive history of dual TCR T cell research, re-evaluate past observations in the context of current knowledge of the immune system, and identify key issues for future study. Read More

Research ethics at the University of Minnesota

We are committed to protecting research participants, upholding ethical standards, and improving our practice at every step of our work.

Learn more about our commitment to research ethics 

Announcements


U of MN Faculty

2:30 p.m. | 2-163 WMBB
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COVID-19 Scientific Daily Update
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Zoom Meetings
**listed below **

Learn to secure your meeting: here
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Monday Seminars

Immunology Journal Club
July 13-Hamilton lab, Jake Hildebrand

9:00-10:00 a.m.|Zoom: here
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MICaB-Immunology Invited Speaker Seminar
Canceled until Fall 2020
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CFI Tea and Talk Time 

2:30-3:00 p.m.| Zoom: here or SIP: here
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Tuesday Seminars

Cancer Center Seminar Series
Check website for Zoom info.

9:00-10:00 a.m. 
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Infection and Immunity Research Conference

1:00-2:00 p.m.| Zoom: 
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COVID-19 Discussion Group
The Immunopathology of COVID-19
July 7, 2020 Topic: 
Discussion Leads:

12:00-1:00 p.m.| Zoom: here
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Wednesday Seminars

Weekly All-Medical School COVID-19 Forum
Post forum questions can be submitted here

9:15-10:00 a.m.| Zoom: here
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Global Immunotalks Seminar Series
Discussion Leads:Carla Rothlin (Yale) and Elina Zuniga (UCSD)

Weekly topic: Limiting Infection-Induced Inflammation by Chris Hunter
For ZOOM info, past recordings and to register: go here

10:00-11:00 a.m.|Zoom: here
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Immunology Supergroup
July 1, 2020-Griffith Lab

1:30-2:30 p.m. | Zoom: here
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Thursday Seminars

MICaB Student Seminar Series
Check calendar for ZOOM info

12:00-1:00 p.m.| Zoom
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CFI Tea and Talk Time 

2:30-3:00 p.m.| Zoom: here or SIP: here
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Lab Hibernation info

Guidance for labs
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Looking for a place to write?

If you are writing and need a quiet place to gather your thoughts, we have a spot for you.

See Annette Bethke, 2-142 WMBB to check out the office key.