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The Center for Immunology is an interdisciplinary research program at the University of Minnesota devoted to advancing the field of immunology and educating future immunologists.

Autoimmunity Cancer Vaccines Cures

 

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The Binstadt Lab in the University of Minnesota’s Center for Immunology seeks a new post-doctoral
fellow. This individual will work together with our team to explore mechanisms of cardiovascular
inflammation in the setting of systemic autoimmunity.

Applicants must hold a Ph.D. degree in biological science and have a recent track record of publication
of first-author peer-reviewed manuscripts.

● Preference will be given to applicants with Ph.D. degrees in Immunology (particularly
Autoimmunity) and/or expertise in Vascular Biology, particularly the role of inflammation in the
cardiovascular system.
● Experience working with small animal models, flow cytometry, immunofluorescent microscopy,
and analysis of transcriptomic data (e.g. scRNASeq) or similar large datasets is preferred.
● Preference will be given to applicants with demonstrated expertise in developing scientific
protocols, scientific writing, and outstanding letters of reference.

Please apply online using job code 340404. Also, email a curriculum vitae and a cover letter to Bryce
Binstadt, MD, Ph.D. Full job description here.

Marc jThe American Association of Immunologists (AAI) has bestowed their highest honor on Dr. Marc Jenkins.  The 2020-21 Lifetime Achievement Award recognizes a deserving AAI member for a career of scientific achievement and for contributions to AAI and fellow immunologists and to the field of immunology.   For more information on all of Dr. Jenkins's achievements go here.  CFI would like to extend our congratulations and thank Dr. Jenkins for his guidance and leadership as well as the inspiration he inspires as a teacher, mentor, and scientist to those not only at our University but worldwide. The Virtual IMMUNOLOGY2021™ will be held May 10–15, the AAI Lifetime Achievement Award will be presented to Dr. Jenkins on Monday, May 10, 2021, at 10:30 a.m Check out the lineup of speakers here: z.umn.edu/6sqe

 

Kris
Dr. Kris Hogquist has been Kris has been named a 2021 distinguished Fellow of the American Association of Immunologists(AAI).  This program is one of the highest honors bestowed by AAI. Members are recognized for their distinguished careers in the field of immunology; the new class of distinguished fellows has shown exceptional leadership to the immunology community at a national or international level; notable distinction as an educator and outstanding scientific contributions, as well as their service to AAI.  CFI would like to congratulate Dr. Hogquist on a well-deserved honor. Meet the class of 2021. The Virtual IMMUNOLOGY2021™ will be held May 10–15, the AAI Distinguished Fellows Class of 2020 and Class of 2021 Acknowledgment will be held on Thursday, May 13, 2021, from 5:00-7:00 p.m. Check out the lineup of speakers here: z.umn.edu/6sqe

 

Marc NAS photo

CFI is honored to announce that our Director Marc Jenkins, PhD has been elected to the National Academy of Sciences. Marc's achievement is especially notable in that it has been over 50 years since a UMN Medical School faculty member has been added to this impressive organization of the country’s leading researchers. The National Academy of Sciences elects new members in recognition of their distinguished and continuing achievements in original research. Membership is a widely accepted mark of excellence in science and is considered one of the highest honors that a scientist can receive. Current NAS membership totals approximately 2,400 members and 500 foreign associates, of which approximately 190 have received Nobel prizes. Dr. Marc Jenkins has led a distinguished career whose scientific endeavors have answered critical questions in the field of immunology…. Marc is an exemplary scientist, educator, mentor, and advisor. To read more about Marc's accomplishments please click here. We are planning a virtual celebration to honor Dr. Jenkins. Please watch for more details on how to join our celebration, dates and time of the celebration will be listed here and on our Twitter account, @CFI_UMN.

  • CD40 Agonist Overcomes T Cell Exhaustion Induced by Chronic Myeloid Cell IL-27 Production in a Pancreatic Cancer Preclinical Model

    The Stromnes lab was recently awarded an RO1 based on the work led by Dr. Adam Burrack. His recent first author  J. Immunol and Cell Report papers have identified a mechanistic basis for T cell exhaustion in pancreatic cancer and a feasible clinical strategy to overcome it.

  • Expansible residence decentralizes immune homeostasis

    While working on his doctoral thesis in the Masopust lab, Sathi Wijeyesinghe found that expansibility and tissue residency are generalizable qualities that underlie immune homeostasis, building on our initial exploration of resident memory T cell durability and maintenance, his "story" can be read in the March 2021 edition of Nature.

  • MHC class II tetramers engineered for enhanced binding to CD4 improve detection of antigen-specific T cells.

    In the May 2021 issue of Nature Biotechnology, a study led by Dr. T. Dileepan from the Jenkins group examined the effect of MHC class II tetramers engineered for enhanced binding, to improve the detection of low-affinity CD4 antigen-specific T cells go.nature.com/337Y6nY

  • T cell memory: Understanding COVID-19

    As the SARS-CoV-2 pandemic has progressed, increasing attention has focused on establishing natural and vaccine-induced immunity against this coronavirus and the disease, COVID-19, that it causes. In the 2021 preprint issue of Immunity, Jarjour, Masopust and Jameson explain the fundamental features of T cell memory and their potential relevance for effective immunity to SARS-CoV-2. Read here
  • Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression

    A study published in Nature Immunology which was led by Jesse Williams has formed new answers regarding atherosclerosis, the build-up of fats, cholesterol and other substances in and on the artery walls. Read here.

  • Thymic regulatory T cells arise via two distinct developmental programs

    The developmental programs that generate a broad repertoire of regulatory T cells (Treg cells) able to respond to both self-antigens and non-self antigens remain unclear. Here the Farrar lab et al. found that mature Treg cells were generated through two distinct developmental programs involving CD25+ Treg cell progenitors and Foxp3lo Treg cell progenitors (Foxp3lo TregP cells). Read more 

Research ethics at the University of Minnesota

We are committed to protecting research participants, upholding ethical standards, and improving our practice at every step of our work.

Learn more about our commitment to research ethics 

Announcements

9:00-10:00am|Zoom:here
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MICaB-Immunology Invited Speaker Seminar

Returns Fall 2021
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CFI Tea and Talk Time
2:30-3:00pm|Zoom:here 
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BGREAT and OPD Seminars:
Check calendar for all events

From Industry's Perspective: What Makes a Great Research Partner?
11:30am – 12:30pm|Register
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9:00-10:00 a.m.|Zoom:here
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Early Career Immunology Digital Seminar Series
Next Meeting: June 8
11:00-12:00 p.m.|Zoom:here
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BGREAT and OPD Seminars:
Check calendar for all events

Navigating USA JOBS
10:00am – 11:30am|Register

SciPhD @ UMN
3pm – 5pm|Register 
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"Novel immunoregulatory molecules coordinating PKC and PKA activities to balance immunity in dendritic cells: Role of Pde1b and AIF1 in cDC1"

MICaB Student Seminar Series
Check calendar for ZOOM info
Returns Fall 2021
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IBP/MD Center Seminar Series

Dr. Christina Camell
12:00-1:00 p.m.| Zoom:here
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BGREAT and OPD Seminars 
Check calendar for all events

Mindsets and the Power of Perspectives
12pm – 1pm|Register

Mindful Communication at Work: An Approach for Creating More Inclusive and Engaged Teams
12pm – 1pm|Register here

SciPhD @ UMN
3pm – 5pm|Register
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Friday Seminars: May 21

BGREAT and OPD Seminars
Check calendar for events

Looking for a place to write?

If you are writing and need a quiet place to gather your thoughts, we have a spot for you.

See Annette Bethke, 2-142 WMBB to check out the office key.