The Center for Immunology is an interdisciplinary research program at the University of Minnesota devoted to advancing the field of immunology and educating future immunologists.
Autoimmunity • Cancer • Vaccines • Cures
Wondering about COVID-19 research and news...
Join REJUS and EWIS for our monthly discussions on race and gender inequality!!
Marc Jenkins recently announced the formation of Restorative Justice for the Underrepresented in Science (ReJUS) at the CFI. ReJUS was born in the wake of the murder of George Floyd, nationwide protests on racial discrimination and discriminatory policing practices including the use of deadly force against black persons. These events have shaken our world, and have been a very painful reminder of our collective silence and complicity in maintaining the status quo and allowing racial injustice to go unchallenged. While centuries of institutionalized racism is daunting to correct as individuals, as a collective of scientists, we can reassess our individual and institutional beliefs, practices, norms, and culture and set them on a more just and equitable course.
23 UMN Faculty Named on 2020 Highly Cited Researchers List
Bryce Binstadt, MD is named director of Pediatric Rheumatology in the Department of Pediatrics
Congratulations to Dr. Bryce Binstadt, he wasPediatric Rheumatology division in the Department of Pediatrics
Dr. Yoji Shimizu has helped launch Faculty Fighting Racism an initiative created as a first step to provide resources for understanding anti-racism and empowering faculty to take action.
New Findings of Atherosclerosis identified in study led by the Williams Lab
AAI bestows their highest honor the Lifetime Achievement Award to Dr. Marc Jenkins
Securing your Zoom meeting
Marc Jenkins elected to the National Academy of Sciences!
CFI is honored to announce that our Director Marc Jenkins, PhD has been elected to the National Academy of SciencesWe are planning a virtual celebration to honor Dr. Jenkins. Please watch for more details on how to join our celebration, dates and time of the celebration will be listed here and on our Twitter account, @CFI_UMN.
Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression
A study published in Nature Immunology which was led by Jesse Williams has formed new answers regarding atherosclerosis, the build-up of fats, cholesterol and other substances in and on the artery walls. Read here.
Naive B Cells with High-Avidity Germline-EncodedAntigen Receptors Produce Persistent IgM+andTransient IgG+Memory B Cells
Immune memory often lasts for life, this is not the case for certain vaccines in some individuals. By studying B cell responses to phycoerythrin, in the June 2018 issue of Immunity, Pape et al. find that memory B cell responses can be shortlived when generated from precursors that experience unusually strong early signals of avid antigen binding via germline-encoded VH elements.
Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory
Using two-photon intravital microscopy to visualize the responses of CD8+ resident memory T cells (Trm cells), Post Doctoral fellows in Masopust, Vezys, and Fife labs found that the Trm cells were highly motile but would pause and undergo in situ division after antigen challenge. Read more
Co-housing with pet store mice changes the immune system of laboratory mice
Nature highlights the work of Lalit Beura, Sara Hamilton, Marc Jenkins, Vaiva Vezys, Steve Jameson, Dave Masopust, et.al. and their evidence of how laboratory rodents can skew immunology research but that "dirty mice" can clean up the results Read more
Thymic regulatory T cells arise via two distinct developmental programs
The developmental programs that generate a broad repertoire of regulatory T cells (Treg cells) able to respond to both self-antigens and non-self antigens remain unclear. Here the Farrar lab et al. found that mature Treg cells were generated through two distinct developmental programs involving CD25+ Treg cell progenitors and Foxp3lo Treg cell progenitors (Foxp3lo TregP cells). Read more
Dual TCR T Cells: Identity Crisis or Multitaskers?
Research ethics at the University of Minnesota
Looking for a place to write?
If you are writing and need a quiet place to gather your thoughts, we have a spot for you.
See Annette Bethke, 2-142 WMBB to check out the office key.