The Center for Immunology is an interdisciplinary research program at the University of Minnesota devoted to advancing the field of immunology and educating future immunologists.
Autoimmunity • Cancer • Vaccines • Cures
Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory
Using two-photon intravital microscopy to visualize the responses of CD8+ resident memory T cells (Trm cells), Post Doctoral fellows in Masopust, Vezys, and Fife labs found that the Trm cells were highly motile but would pause and undergo in situ division after antigen challenge. Read more
Co-housing with pet store mice changes the immune system of laboratory mice
Nature highlights the work of Lalit Beura, Sara Hamilton, Marc Jenkins, Vaiva Vezys, Steve Jameson, Dave Masopust, et.al. and their evidence of how laboratory rodents can skew immunology research but that "dirty mice" can clean up the results Read more
Cutting Edge: Dual TCRa Expression Poses an Autoimmune Hazard by Limiting Regulatory T cell Generation
In cutting edge research performed by the students and Post Doctoral fellows in the labs of Fife, Hogquist and Binstadt the hypothesis that dual TCR expression can promote autoimmunity by limiting agonist selection of self-reactive thymocytes is revisited . Read more
Jason Mitchell and Brian Fife show Tumor specific T cells (red and green) interacting with B16 Tumor cells (blue) and CD11c YFP DCs (yellow)
CD8αα+ Intraepithelial Lymphocytes Arise from Two Major Thymic Precursors
In an article published in Nature Immunology, Post Doctoral Fellows Ruscher and Lee from the Hoquist and Jameson lab wanted to better define the thymic IEL precursor, and were able to provide an important foundation for understanding the biology of CD8αα IELs. Read More
CD301b/MGL2+ Mononuclear Phagocytes Orchestrate Autoimmune Cardiac Valve Inflammation and Fibrosis
CD301b/MGL2+ MNP's are key drivers of autoimmune MVD in K/B.g7 mice and in human RHD. Research led by MSTP student Lee Meier in the lab of Dr. B. Binstadt define key inflammatory molecules that drive MVD in hopes of identifying potential therapeutic targets for clinical use. Read More
Dr. Sara Hamilton-Hart awarded the 2018 Careers in Immunology Fellowship by the American Association of Immunologists (AAI)
Dr. Sara Hamilton Hart has been awarded an American Association of Immunologists 2018 Careers in Immunology Fellowship. The fellowship supports the career development of young scientists by providing eligible PIs with one year of salary support for a trainee in their lab. Postdoctoral trainee, Dr. Mathew Huggins will receive salary support for his work on the effect of previous immune experience on T cell functionality and how this alters the ability to respond to new challenges in Hamilton Hart’s laboratory. Congratulations to both Drs. Hamilton Hart and Huggins.
Congressman Emmer visits CFI
On April 30th, the Center for Immunology was honored to host Congressman Emmer to Tea and Talk. Dr. Nathan Schuldt invited Congressman Emmer to tour our facility after visiting the congressman in Washington D.C. as part of the American Association of Immunologists Public Policy Fellowship Program. After a tour and discussion on the importance of basic research to spur advancements in health care, Congressman Emmer greeted CFI staff and opened the floor to questions. The visit was a great opportunity to showcase to the Congressman our important role in scientific research, while creating an open dialogue about the need for continued support for NIH and science funding.
The American Association of Immunologists (AAI) honors Dr. Marc Jenkins with the 2018 Excellence in Mentoring Award
The AAI Excellance in Mentoring Award honors the recipient's exemplary career contributions to the professional development of their trainees and the importance of the mentor-trainee relationship. This year the AAI honored Dr. Marc Jenkins and his impressive contributions to the field of Immunology through his mentorship of future generations of scientists. Dr. Jenkins received his award at the 2018 AAI annual meeting in Austin, TX from May 4-8, 2018.
Registration is open for Chainbreaker18
The event was also memorable for a performance by Minnesota native and Gear Daddies legend Martin Zellar. Even better, our own Yoji Shimizu of Outliers fame joined in on a couple of tunes.
CFI in partnership with local theatre professionals present: TheRelational Experience Development (R.E.D.) Seminar Series
Scientists are in the professional communication business. We write papers to that we hope other scientists will find useful. We give seminars to generate interest in our work and to engage other scientists in conversation and possible collaborations. Everyone has experienced the buzz of excitement a great talk can generate. Remarkably, despite the importance of this form of communication, there are few opportunities in scientific training to learn this discipline. Few scientists even consider that the art of oral communication is an academic discipline in its own right.
As part of a multi-year collaboration the Center for Immunology, CTSI, and the Masonic Cancer Center is committed to providing the best opportunities to all our trainees in learning the art of oral presentation. To achieve this goal we have partnered with Narrative Pros Coaching Agency The yearly seminar series provides the principles of effective oral communication, examines deeper topics, and provides individual feedback. For more information or to view past seminars, click here.
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