cfi


The Center for Immunology is an interdisciplinary research program at the University of Minnesota devoted to advancing the field of immunology and educating future immunologists.

Autoimmunity Cancer Vaccines Cures

 

Latest News
 

Mark your calendars: CFI Diversity Workshop Feb. 3, 2021

The Office of Equity and Diversity will be conducting a workshop for all faculty, staff, and trainees at the CFI. The title of the workshop is "My Role in Equity and Diversity work" and it will take place on Wednesday, Feb 3rd from 10:00 am-12:00pm. Please go to https://forms.gle/28jiw8rXWgVD2PF49 and register for this important event.  Zoom link: here  Password: 758G2B. 

Marc NAS photo

CFI is honored to announce that our Director Marc Jenkins, PhD has been elected to the National Academy of Sciences. Marc's achievement is especially notable in that it has been over 50 years since a UMN Medical School faculty member has been added to this impressive organization of the country’s leading researchers. The National Academy of Sciences elects new members in recognition of their distinguished and continuing achievements in original research. Membership is a widely accepted mark of excellence in science and is considered one of the highest honors that a scientist can receive. Current NAS membership totals approximately 2,400 members and 500 foreign associates, of which approximately 190 have received Nobel prizes. Dr. Marc Jenkins has led a distinguished career whose scientific endeavors have answered critical questions in the field of immunology…. Marc is an exemplary scientist, educator, mentor, and advisor. To read more about Marc's accomplishments please click here. We are planning a virtual celebration to honor Dr. Jenkins. Please watch for more details on how to join our celebration, dates and time of the celebration will be listed here and on our Twitter account, @CFI_UMN.

  • T cell memory: Understanding COVID-19

    As the SARS-CoV-2 pandemic has progressed, increasing attention has focused on establishing natural and vaccine-induced immunity against this coronavirus and the disease, COVID-19, that it causes. In the 2021 preprint issue of Immunity, Jarjour, Masopust and Jameson explain the fundamental features of T cell memory and their potential relevance for effective immunity to SARS-CoV-2. Read here
  • Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression

    A study published in Nature Immunology which was led by Jesse Williams has formed new answers regarding atherosclerosis, the build-up of fats, cholesterol and other substances in and on the artery walls. Read here.

  • Beura, Et Al, Nature Immunology paper 19,173-182 (2018)

    Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory

    Using two-photon intravital microscopy to visualize the responses of CD8resident memory T cells (Trm cells), Post Doctoral fellows in Masopust, Vezys, and Fife labs found that the Trm cells were highly motile but would pause and undergo in situ division after antigen challenge. Read more

  • Co-housing with pet store mice changes the immune system of laboratory mice

     Nature  highlights the work of Lalit Beura, Sara Hamilton, Marc Jenkins, Vaiva Vezys, Steve Jameson, Dave Masopust, et.al. and their evidence of how laboratory rodents can skew immunology research but that "dirty mice" can clean up the results. Read more

  • Thymic regulatory T cells arise via two distinct developmental programs

    The developmental programs that generate a broad repertoire of regulatory T cells (Treg cells) able to respond to both self-antigens and non-self antigens remain unclear. Here the Farrar lab et al. found that mature Treg cells were generated through two distinct developmental programs involving CD25+ Treg cell progenitors and Foxp3lo Treg cell progenitors (Foxp3lo TregP cells). Read more 

  • Dual TCR T Cells: Identity Crisis or Multitaskers?

    In this study, Drs. Binstadt and Schuldt aim to provide a brief but comprehensive history of dual TCR T cell research, re-evaluate past observations in the context of current knowledge of the immune system, and identify key issues for future study. Read More

Research ethics at the University of Minnesota

We are committed to protecting research participants, upholding ethical standards, and improving our practice at every step of our work.

Learn more about our commitment to research ethics 

Announcements

Immunology Journal Club
Jameson Lab-Emily Truckenbrod

9:00-10:00 a.m.|Zoom:here
__________________
MICaB-Immunology Invited Speaker Seminar
 

BioFrontiers Institute, University of Colorado, Boulder, Boulder, CO

"Secrets of transcriptional regulation uncovered from nascent transcription"

12:00-1:00 p.m.|Zoom: here
___________________
CFI Tea and Talk Time 

2:30-3:00 p.m.|Zoom:here 
___________________________

Tues. Seminars: Feb 23

Cancer Center Seminar Series
Check website for Zoom info.

9:00-10:00 a.m.|Zoom: here
___________________
BGREAT and OPD Seminars:
Check calendar for all events

Scientific Program & Project Management
5:00–5:00 p.m.|Register here
____________________________

Wed. Seminars: Feb. 24

9:15-10:00 a.m.| Zoom:here
____________________
BGREAT and OPD Seminars:
Check calendar for all events

Write Now!
9:00-11:30 a.m.|Register here
____________________
Immunology Supergroup
Schuldt Lab

1:30-2:30 p.m.|Zoom:here
Passcode: 744022
____________________
Microbiome Supergroup Seminar

Dr. Ryan Demmer
 "The digestive tract microbiome as a contributor to diabetes and heart failure etiology"
and
Dr. Abigail Johnson
 "Linking diet with the microbiome"

3:00-4:00|Zoom here
_____________________________

Thurs. Seminars: Feb. 25

MICaB Student Seminar Series
Check calendar for ZOOM info

Jenna Johnson
Advisor: Geoff Hart

“Characterization of adaptive NK cells in malaria”

12:00-1:00 p.m.| Zoom:here
__________________
IBP/MD Center Seminar Series

Dr. Marcia Haigis

12:00-1:00 p.m.| Zoom:here
___________________
BGREAT and OPD Seminars 
Check calendar for all events

When to Say No and When to Say Yes
12:00-1:00 p.m.|Register here

Imposter Syndrome: Addressing it Individually and the Attributes of Organizations that Remedy it
4:45–6:15 p.m.|Register here

How to Find and Cultivate Industry Mentor
5:00– 6:00 p.m.|Register here
____________________________

Friday Seminars: Feb. 26

Pharmacology Webinar Series

Minoli Perera PharmD, PhD
Associate Professor, Department of Pharmacology, Northwestern University

"Discoveries in the African Ancestry Genome: Precision Medicine for All"

10:00-11:00 a.m.| Zoom:here
____________________
BGREAT and OPD Seminars 
Check calendar for all events

4 Things to consider if you want to start a business or be a freelancer
11:00-12:00 p.m.|Register here

YMOC - Optional Discussion for Module 1
1:30-2:30 p.m.|Zoom here
____________________________

Save the dates:

March 15, 2021
Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA
Host: Matthew Aliota, PhD 
 
"Persistence of Zika virus in the male reproductive tract"
12:00-1:00 p.m.|Zoom: here
_____________________________

Lab Hibernation info
Guidance for labs
_____________________________

Looking for a place to write?

If you are writing and need a quiet place to gather your thoughts, we have a spot for you.

See Annette Bethke, 2-142 WMBB to check out the office key.