The Center for Immunology is an interdisciplinary research program at the University of Minnesota devoted to advancing the field of immunology and educating future immunologists.
Autoimmunity • Cancer • Vaccines • Cures
Wondering about COVID-19 research and news...
The American College of Rheumatology awards Bryce Binstadt, M.D., Ph.D. the 2021 Award of Distinction for Excellence in Investigative Mentoring
Each year the American College of Rheumatology recognizes its members' outstanding contributions to the field of rheumatology through an awards program. This year an excellent researcher, instructor, mentor, practitioner & leader was awarded the 2021 Excellence in Investigative Mentoring Award. Bryce Binstadt embodies the Excellence in Investigative Mentoring Award. This award recognizes the importance of the mentor/mentee relationship. A dedicated mentor can significantly influence the successful development and career of a mentee. This award honors an active ACR or ARP member for their contributions to the rheumatology profession through outstanding and ongoing mentoring. Funding support for this award of distinction is provided by the Rheumatology Research Foundation. Dr. Binstadt He has a successful lab that is working on understanding the pathogenesis of autoimmune diseases with particular emphasis on immune-mediated cardiovascular disease, he is a clinical pediatric rheumatologist who cares for children with arthritis, lupus, dermatomyositis, and related rheumatologic disorders,
AIRE to host Postdoc Grant Writing Seminar & Workshop
AIRE is excited to announce an upcoming workshop focused on applying for postdoc fellowships. We hope this will be a useful resource for postdocs who are unable to utilize graduate grant resources but aren't quite ready for advanced career grants (K99s, etc.) that are reviewed in CFI's grant review group.
The Workshop will consist of 3 sessions (weeks of 9/27, 10/11, & 11/1) in which small groups of 3-4 applicants will meet with one faculty and one postdoc mentor to review and provide peer-peer feedback on various sections within each applicants' grant (more specifically: Specific Aims, Training Plan, Research Plan). Please note, this workshop is designed specifically for postdocs applying for fellowships (F32s, ACS fellowships, etc.) and late-stage graduate students interested in applying for the NIH F99 transition grant or preparing for postdoc grants. If you are interested in the workshop, please RSVP ASAP to ensure that we are able to provide sufficient mentorship and support for all interested participants!
RSVP here: https://z.umn.edu/CFI-2021-grant-writing Find attached the full flyer with information.
CFI Postdoctoral Fellows honored as part of National Postdoc Appreciation Week
Dr. Milagros Silva M
Meagan Rollins Named 2021-2022 Dennis W. Watson Fellowship Recipient
CFI would like to congratulate Meagan Rollins, the recipient of the 2021-2022 Dennis W. Watson fellowship. The Watson Fellowship is an annual competitive award for microbiology track students beginning their fourth year of study in the MICaB program and have as their faculty advisor a member of the microbiology faculty or MICaB microbiology track faculty. The student receives a one-year non-renewable fellowship in addition to a $500 cash award.
Meagan is a fourth-year graduate student in Ingunn Stromnes lab. Her current research emphasis is understanding mechanisms of T cell exhaustion and engineered T cell immunotherapy for the treatment of pancreatic cancer.
Congratulations to Lucy Sjaastad, 2021 Pfizer Junior Investigator Award for Most Promising Research Presentations
Lucy Sjaastad a 4th-year MICAB graduate student in Dr. Michael Farrar’s lab was awarded the Pfizer Junior Investigator Award for Most Promising Research PresentationCytokines 2021 Hybrid MeetingPfizernknown. Using a novel mouse model that enables inducible depletion of ISG-Tregs, Lucy and her colleagues aim to dissect the function of these Tregs during influenza infection.
Milcah Scott is awarded a Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship
CFI would like to congratulate Milcah Scott, a predoctoral student in the Masopust Lab. Milcah was awarded the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship for her work on a suite of contemporary and complementary whole animal, cellular and molecular approaches to better define the transcriptional programs and phenotypes of stringently-identified, bona fide tissue resident memory CD8 T cells (TRM). Refined analyses of TRM will broaden our understanding of how TRM are generated and maintained in tissues and are key to addressing deficiencies in our understanding of how (TRM) effect pathogen protection, tumor control, and autoimmune pathogenesis. The purpose of the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship award is to enable promising predoctoral students to obtain individualized, mentored research training from outstanding faculty sponsors while conducting dissertation research in scientific health-related fields to enhance the individual’s potential to develop into a productive, independent research scientist.
Congratulations to Dr. JT Greene for his American Cancer Society postdoctoral fellowship
J.T. Greene, Ph.D. from the Freedman labthe American Cancer Society to support his ongoing research and training. The Cancer Society awards researchers who are within 3 years of receiving a doctoral degree initial funding to start training for an independent career in cancer research. J.T. was also awarded The Ben G. Zimmerman Travel Award from the Department of Pharmacology, this award supports the participation (poster or oral presentation) of graduate students and postdoctoral trainees at scientific conferences.
Join AIRE and EWIS for our monthly discussions on race and gender inequality!!
Securing your Zoom meeting
Marc Jenkins elected to the National Academy of Sciences and AAI awards him their highest honor: The Lifetime Achievement Award!
AAI bestows their highest honor the Lifetime Achievement Award to Dr. Marc Jenkins
The American Association of Immunologists (AAI) has bestowed their highest honor on Dr. Marc Jenkins. The 2020-21 Lifetime Achievement Awardhere. CFI would like to extend our congratulations and thank Dr. Jenkins for his guidance and leadership as well as the inspiration he inspires as a teacher, mentor, and scientist to those not only at our University but worldwide. The Virtual IMMUNOLOGY2021™ was held May 10–15, if you missed the awards presentation, click here
Enhanced CD4+ and CD8+ T cell infiltrate within convex hull defined pancreatic islet borders as autoimmune diabetes progresses
Nature's Scientific Reports, August 25, 2021 issue has an article by Alex Dwyer in the Fife lab on a new process to identify islet damage where he introduces an automated convex hull-based analytical procedure using a macro written in FIJI for inflammation. This new tool could elevate inflammation for diabetes assessment and inflammation in general. Read more here: https://z.umn.edu/72ty
CD40 Agonist Overcomes T Cell Exhaustion Induced by Chronic Myeloid Cell IL-27 Production in a Pancreatic Cancer Preclinical Model
The Stromnes lab was recently awarded an RO1 based on the work led by Dr. Adam Burrack. His recent first author J. Immunol and Cell Report papers have identified a mechanistic basis for T cell exhaustion in pancreatic cancer and a feasible clinical strategy to overcome it.
Expansible residence decentralizes immune homeostasis
While working on his doctoral thesis in the Masopust lab, Sathi Wijeyesinghe found that expansibility and tissue residency are generalizable qualities that underlie immune homeostasis, building on our initial exploration of resident memory T cell durability and maintenance, his "story" can be read in the March 2021 edition of Nature.
MHC class II tetramers engineered for enhanced binding to CD4 improve detection of antigen-specific T cells.
T cell memory: Understanding COVID-19As the SARS-CoV-2 pandemic has progressed, increasing attention has focused on establishing natural and vaccine-induced immunity against this coronavirus and the disease, COVID-19, that it causes. In the 2021 preprint issue of Immunity, Jarjour, Masopust and Jameson explain the fundamental features of T cell memory and their potential relevance for effective immunity to SARS-CoV-2. Read here
Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression
A study published in Nature Immunology which was led by Jesse Williams has formed new answers regarding atherosclerosis, the build-up of fats, cholesterol and other substances in and on the artery walls. Read here.
Research ethics at the University of Minnesota
CFI Fall Retreat
9:00am-6:00pm|Huntington Bank Stadium
Immunology Journal Club
**Hybrid this week**
MICaB-Immunology Invited Speaker Seminar
**Virtual this week**
12:00-1:00 pm|1-125 CCRB|Zoom
CFI Tea and Talk Time
calendarfor all eventsCheck
Too Creative for Science?
2pm – 3pm|Register
Tues. Seminars: Oct. 26
Erin Marcotte, MPH, PhD
Assistant Professor-Pediatrics, UMN
Melody Swartz, Ph.D.
Professor of Molecular Engineering, University of Chicago
“Immunoregulatory Roles of Lymphatic Vessels in Cancer and Opportunities for Immunoengineering”
12:00-1:00pm, Mississippi Room, Coffman
AIRE/CFI Invited Postdoctoral Fellow Seminar Series
Ye-Ji Bang, Ph.D.
Dept. of Immunology,UT Southwestern
"Microbiota-induced vitamin A transport and its role in the intestinal immunity"
Wed. Seminars: Oct. 27
Developing a Teaching Philosophy and Crafting Your Teaching Statement
11am – 12pm|
Lillehei Heart Institute Lecture Series
Bradley A. Maron, MD
Associate Professor of Medicine, Harvard Medical School
Thurs. Seminars: Oct. 28
Advisor: Mike Farrar
“Role of nuclear corepressors in T helper cell development and function”
12:00-1:00pm|1-110 LRB/MTRF or
IBP/MD Center Seminar Series
Dr. Christina Pacak
Exploring the Intersections of Leadership, Equity, Inclusion, & YOU
Pursuing a Career Abroad - Where to Start?
Friday Seminars: Oct. 29
Alessandro Bartolomucci, PhD
Associate Professor,IBP, UMN
"From molecular evolution to pharmacotherapies: a tale of two ligands (C3a, TLQP-21) and one receptor (C3aR1)"
Kris Hogquist, PhD
Professor, LMP, UMN
"Educating T cells"
November 1, 2021
2021 MICaB invited Speaker Seminar
Virtual via Zoom
Teresa Diloreno, PhD
Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY
Host: Brian Fife