The Center for Immunology is an interdisciplinary research program at the University of Minnesota devoted to advancing the field of immunology and educating future immunologists.
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Marc Jenkins elected to the National Academy of Sciences!
CFI is honored to announce that our Director Marc Jenkins, PhD has been elected to the National Academy of SciencesWe are planning a virtual celebration to honor Dr. Jenkins. Please watch for more details on how to join our celebration, dates and time of the celebration will be listed here and on our Twitter account, @CFI_UMN.
Wondering about COVID-19 research and news...
As a result of the increased use of Zoom meetings globally, they have become a target foRead about how to Secure Your Zoom Meetingwatch a short demonstration of In-Meeting Tools to Secure your Zoom Meetings
Dr. Harry Orr earned the 2020 Carole J. Bland Outstanding Faculty Mentor Award. The award honors faculty who serve as role models for each other, promote the professional development of others and creates a supportive, positive working environment. Bland was a long-time faculty member in the Department of Family Medicine and Community Health. The full announcement is here.
Drs. Xavier Revelo and Haiguang Wang have been awarded anAmerican Association of Immunologists 2020 Careers in Immunology FellowshipThe AAI Careers in Immunology Fellowship Program elopment of young scientists by providing eligible PIs with one year of salary support for a trainee in their lab. Postdoctoral trainee, Dr. Wang will receive salary support for his work in the Revelo lab beginning in August. Congratulations to both Drs. Revelo and Wang. For more information on the work being done in Dr. Revelo's lab click here. We would also like to welcome Haiguang back to Minnesota! He originally trained in Kris Hogquist's lab before doing his first post doc in Dario Vignali's lab at the University of Pittsburgh, PA.
CFI would like to Congratulate Dr. David Masopust and Dr. Ryan Langlois on their recent awards and honors. Dr. David Masopust, was named as one of the 2020 Distinguished McKnight University Professors. The Distinguished McKnight University Professorship program recognizes outstanding mid-career faculty members who have recently achieved full professor status, especially those who have made significant advances in their careers at the University of Minnesota, whose work and reputation are identified with the University, and whose accomplishments have brought renown and prestige to Minnesota and to their scholarly fields. Dr. Ryan Langlois has been named a 2020 McKnight Presidential Fellow. The McKnight Presidential Fellows Program is a three-year award given to exceptional faculty who have just achieved tenure and promotion to associate professor, to recognize their accomplishments and support their ongoing research and scholarship. It recognizes recipients who are recommended by their college dean and chosen at the discretion of the executive vice president and provost based on excellence in research and scholarship, leadership, potential to build top-tier programs, and ability to advance University of Minnesota priorities.
Ben Brian is the winner of 2 Medical school awards, he won the 2020 the Veneziale-Steer Award, which recognizes outstanding basic scientific research by a graduate student or a medical student in the field of cellular growth regulation. Ben also was one of the recipients of the 2020 J. Jacob Kaplan award for his work in immunology in diagnosis and treatment of cancer . This award is presented annually for the most meritorious student papers on either clinical or basic medical research. The awards are intended to encourage and recognize scholarly achievement in medical research by young investigators at the University of Minnesota Medical School.Pharmacology Graduate StudentTanya Freedman
CFI would also like to recognize and congratulate our colleague and form@ member Lalit Beura, Assistant Professor of Molecular Microbiology and Immunolog@2020 Searle Scholar is a career development award made annually to 15 US faculty in the first or second year of their first tenure-track assistant professor position in biomedical research, medicine, chemistry, and the biological sciences. The award recognizes faculty who are considered most promising and have made "important, innovative research" contributions and who have the potential for making continuing significant contributions.
Congratulations to all the recipients!!
AAI bestows their highest honor the Lifetime Achievement Award to Dr. Marc Jenkins
The American Association of Immunologists (AAI) has bestowed their highest honor on Dr. Marc Jenkins. The 2020 Lifetime Achievement Award recognizes a deserving AAI member for a career of scientific achievement and for contributions to AAI and fellow immunologists and to the field of immunology. For more information on all of Dr. Jenkins's achievements go here. CFI would like to extend our congratulations and thank Dr. Jenkins for his guidance and leadership as well as the inspiration he inspires as a teacher, mentor, and scientist to those not only at our University but worldwide.
The Center for Immunology proudly hosted its first-ever Alumni Celebration
Naive B Cells with High-Avidity Germline-EncodedAntigen Receptors Produce Persistent IgM+andTransient IgG+Memory B Cells
Immune memory often lasts for life, this is not the case for certain vaccines in some individuals. By studying B cell responses to phycoerythrin, in the June 2018 issue of Immunity, Pape et al. find that memory B cell responses can be shortlived when generated from precursors that experience unusually strong early signals of avid antigen binding via germline-encoded VH elements.
Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory
Using two-photon intravital microscopy to visualize the responses of CD8+ resident memory T cells (Trm cells), Post Doctoral fellows in Masopust, Vezys, and Fife labs found that the Trm cells were highly motile but would pause and undergo in situ division after antigen challenge. Read more
Co-housing with pet store mice changes the immune system of laboratory mice
Nature highlights the work of Lalit Beura, Sara Hamilton, Marc Jenkins, Vaiva Vezys, Steve Jameson, Dave Masopust, et.al. and their evidence of how laboratory rodents can skew immunology research but that "dirty mice" can clean up the results Read more
Thymic regulatory T cells arise via two distinct developmental programs
The developmental programs that generate a broad repertoire of regulatory T cells (Treg cells) able to respond to both self-antigens and non-self antigens remain unclear. Here the Farrar lab et al. found that mature Treg cells were generated through two distinct developmental programs involving CD25+ Treg cell progenitors and Foxp3lo Treg cell progenitors (Foxp3lo TregP cells). Read more
Chrysalis: A New Method for High-Throughput Histo-Cytometry Analysis of Images and Movies
Advances in imaging have led to the development of powerful multispectral, quantitative imaging techniques, like histo-cytometry. The utility of this approach is limited, however, by the need for time-consuming manual image analysis. In an effort to address the time issue, Kotov and Pengo et al. created the software Chrysalis along with a suite of Imaris Xtensions to batch image processing and analysis to automate the processing workflow for confocal, epi-fluorescence, and two-photon microscopy images.
Dual TCR T Cells: Identity Crisis or Multitaskers?
Research ethics at the University of Minnesota
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Immunology Journal Club
July 13-Hamilton lab, Jake Hildebrand
9:00-10:00 a.m.|Zoom: here
Canceled until Fall 2020
CFI Tea and Talk Time
2:30-3:00 p.m.| Zoom:hereor SIP: ___________________________
COVID-19 Discussion Group
The Immunopathology of COVID-19
July 7, 2020 Topic:
12:00-1:00 p.m.|___________________________ Zoom:
Weekly All-Medical School COVID-19 Forum
Post forum questions can be submitted here
9:15-10:00 a.m.| Zoom:here
Global Immunotalks Seminar Series
Discussion Leads:Carla Rothlin (Yale) and Elina Zuniga (UCSD)
Weekly topic: Limiting Infection-Induced Inflammation by Chris Hunter
For ZOOM info, past recordings and to register: go here
10:00-11:00 a.m.|Zoom: here
July 1, 2020-Griffith Lab
Lab Hibernation info
Looking for a place to write?
If you are writing and need a quiet place to gather your thoughts, we have a spot for you.
See Annette Bethke, 2-142 WMBB to check out the office key.