The Center for Immunology produces an immense amount of research each year.  The data produced is comprehensive and timely to research across the globe.  Our research is supported by Government, Commercial and Industrial grants and private funds and is produced in our state of the art research facilities.  The research is carried out by faculty members, visiting scholars, post-doctoral fellows, graduate and undergraduate students and technicians. The Center for Immunology also has a strong collaboration history with colleagues at other Universities and research companies worldwide.


 To honor Center for Immunology faculty with 200 or more citations on one paper we have created our wall of honor. 


View the Wall of Honor


2018 publications

Identification of Cellular Sources of IL-2 Needed for Regulatory T Cell Development and Homeostasis.
Owen DL, Mahmud SA, Vang KB, Kelly RM, Blazar BR, Smith KA, Farrar MA.
J Immunol. 2018 May 4. pii: ji1800097. doi: 10.4049/jimmunol.1800097. [Epub ahead of print]

Is fecal microbiota transplantation a temporary patch for treatment of Clostridium difficile infection or a new frontier of therapeutics?
Khoruts A.
Expert Rev Gastroenterol Hepatol. 2018 May;12(5):435-438. doi: 10.1080/17474124.2018.1465818. Epub 2018 Apr 20.No abstract available.

The Contribution of Autoantibodies to Inflammatory Cardiovascular Pathology.
Meier LA, Binstadt BA.
Front Immunol. 2018 Apr 27;9:911. doi: 10.3389/fimmu.2018.00911. eCollection 2018. Review.
PMID: 29755478

What Is the Predictive Value of Animal Models for Vaccine Efficacy in Humans? Reevaluating the Potential of Mouse Models for the Human Immune System.
Jameson SC, Masopust D.
Cold Spring Harb Perspect Biol. 2018 Apr 2;10(4). pii: a029132. doi: 10.1101/cshperspect.a029132. Review.

Regulatory CD4+ T Cells Recognize MHC-II-Restricted Peptide Epitopes of Apolipoprotein B.
Kimura T, Kobiyama K, Winkels H, Tse K, Miller J, Vassallo M, Wolf D, Ryden C, Orecchioni M, Dileepan T, Jenkins MK, James EA, Kwok WW, Hanna DB, Kaplan RC, Strickler HD, Durkin HG, Kassaye SG, Karim R, Tien PC, Landay AL, Gange SJ, Sidney J, Sette A, Ley K.
Circulation. 2018 Mar 27. pii: CIRCULATIONAHA.117.031420. doi: 10.1161/CIRCULATIONAHA.117.031420. [Epub ahead of print]

Interleukin-15 Complex Treatment Protects Mice from Cerebral Malaria by Inducing Interleukin-10-Producing Natural Killer Cells.
Burrack KS, Huggins MA, Taras E, Dougherty P, Henzler CM, Yang R, Alter S, Jeng EK, Wong HC, Felices M, Cichocki F, Miller JS, Hart GT, Johnson AJ, Jameson SC, Hamilton SE.
Immunity. 2018 Mar 20. pii: S1074-7613(18)30088-8. doi: 10.1016/j.immuni.2018.03.012. [Epub ahead of print]

Many Th Cell Subsets Have Fas Ligand-Dependent Cytotoxic Potential.
Kotov DI, Kotov JA, Goldberg MF, Jenkins MK.
J Immunol. 2018 Mar 15;200(6):2004-2012. doi: 10.4049/jimmunol.1700420. Epub 2018 Feb 7.

Antibiotic-induced Disruption of Intestinal Microbiota Contributes to Failure of Vertical Sleeve Gastrectomy.
Jahansouz C, Staley C, Kizy S, Xu H, Hertzel AV, Coryell J, Singroy S, Hamilton M, DuRand M, Bernlohr DA, Sadowsky MJ, Khoruts A, Ikramuddin S.
Ann Surg. 2018 Mar 8. doi: 10.1097/SLA.0000000000002729. [Epub ahead of print]

Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: implications for B-cell selection.
Lloyd KA, Steen J, Amara K, Titcombe PJ, Israelsson L, Lundström SL, Zhou D, Zubarev RA, Reed E, Piccoli L, Gabay C, Lanzavecchia A, Baeten D, Lundberg K, Mueller DL, Klareskog L, Malmström V, Grönwall C.
Eur J Immunol. 2018 Mar 7. doi: 10.1002/eji.201747446. [Epub ahead of print]
PMID: 29512823

Intravenous Labeling and Analysis of the Content of Thymic Perivascular Spaces.
Ruscher R, Hogquist KA.
Bio Protoc. 2018 Mar 5;8(5). pii: e2757. doi: 10.21769/bioprotoc.2757.
PMID: 29644257

RelB-Deficient Dendritic Cells Promote the Development of Spontaneous Allergic Airway Inflammation.
Nair PM, Starkey MR, Haw TJ, Ruscher R, Liu G, Maradana MR, Thomas R, O'Sullivan BJ, Hansbro PM.
Am J Respir Cell Mol Biol. 2018 Mar;58(3):352-365. doi: 10.1165/rcmb.2017-0242OC.

Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset.
Hülsdünker J, Ottmüller KJ, Neeff HP, Koyama M, Gao Z, Thomas OS, Follo M, Al-Ahmad A, Prinz G, Duquesne S, Dierbach H, Kirschnek S, Lämmermann T, Blaser MJ, Fife BT, Blazar BR, Beilhack A, Hill GR, Häcker G, Zeiser R.
Blood. 2018 Apr 19;131(16):1858-1869. doi: 10.1182/blood-2017-10-812891. Epub 2018 Feb 20.

T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells.
Beura LK, Wijeyesinghe S, Thompson EA, Macchietto MG, Rosato PC, Pierson MJ, Schenkel JM, Mitchell JS, Vezys V, Fife BT, Shen S, Masopust D.
Immunity. 2018 Feb 20;48(2):327-338.e5. doi: 10.1016/j.immuni.2018.01.015.
PMID: 29466758

Understanding Subset Diversity in T Cell Memory.
Jameson SC, Masopust D.
Immunity. 2018 Feb 20;48(2):214-226. doi: 10.1016/j.immuni.2018.02.010. Review.
PMID: 29466754

Strain Tracking Reveals the Determinants of Bacterial Engraftment in the Human Gut Following Fecal Microbiota Transplantation.
Smillie CS, Sauk J, Gevers D, Friedman J, Sung J, Youngster I, Hohmann EL, Staley C, Khoruts A, Sadowsky MJ, Allegretti JR, Smith MB, Xavier RJ, Alm EJ.
Cell Host Microbe. 2018 Feb 14;23(2):229-240.e5. doi: 10.1016/j.chom.2018.01.003.

CD301b/MGL2+ Mononuclear Phagocytes Orchestrate Autoimmune Cardiac Valve Inflammation and Fibrosis.
Meier LA, Auger JL, Engelson BJ, Cowan HM, Breed ER, Gonzalez-Torres MI, Boyer JD, Verma M, Marath A, Binstadt BA.
Circulation. 2018 Jan 31. pii: CIRCULATIONAHA.117.033144. doi: 10.1161/CIRCULATIONAHA.117.033144. [Epub ahead of print] 
PMID: 29386201

Cutting Edge: Allograft Rejection Is Associated with Weak T Cell Responses to Many Different Graft Leukocyte-Derived Peptides.
Burrack AL, Malhotra D, Dileepan T, Osum KC, Swanson LA, Fife BT, Jenkins MK.
J Immunol. 2018 Jan 15;200(2):477-482. doi: 10.4049/jimmunol.1701434. Epub 2017 Dec 18.
PMID: 29255075

Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory.
Beura LK, Mitchell JS, Thompson EA, Schenkel JM, Mohammed J, Wijeyesinghe S, Fonseca R, Burbach BJ, Hickman HD, Vezys V, Fife BT, Masopust D.
Nat Immunol. 2018 Feb;19(2):173-182. doi: 10.1038/s41590-017-0029-3. Epub 2018 Jan 8.
PMID: 29311694

Do Memory B Cells Form Secondary Germinal Centers? It Depends.
Pape KA, Jenkins MK.
Cold Spring Harb Perspect Biol. 2018 Jan 2;10(1). pii: a029116. doi: 10.1101/cshperspect.a029116. Review.
PMID: 28320756

Functional Genomics of Host-Microbiome Interactions in Humans.
Luca F, Kupfer SS, Knights D, Khoruts A, Blekhman R.
Trends Genet. 2018 Jan;34(1):30-40. doi: 10.1016/j.tig.2017.10.001. Epub 2017 Oct 26. Review.
PMID: 29107345

2017 publications

Is a Human CD8 T-Cell Vaccine Possible, and if So, What Would It Take? CD8 T-Cell Vaccines: To B or Not to B?
Beura LK, Jameson SC, Masopust D.
Cold Spring Harb Perspect Biol. 2017 Dec 18. pii: a028910. doi: 10.1101/cshperspect.a028910. [Epub ahead of print]
PMID: 29254982

Increased Effector Memory Insulin-Specific CD4+T-cells Correlate with Insulin Autoantibodies in Recent-Onset Type 1 Diabetic Patients.
Spanier JA, Sahli NL, Wilson JC, Martinov T, Dileepan T, Burrack AL, Finger EB, Blazar BR, Michels AW, Moran A, Jenkins MK, Fife BT.
Diabetes. 2017 Dec;66(12):3051-3060. doi: 10.2337/db17-0666. Epub 2017 Aug 25
PMID: 28842400

Directing T cell fate: How thymic antigen presenting cells coordinate thymocyte selection.
Breed ER, Lee ST, Hogquist KA.
Semin Cell Dev Biol. 2017 Aug 9. pii: S1084-9521(16)30452-9. doi: 10.1016/j.semcdb.2017.07.045. [Epub ahead of print] Review.
PMID: 28800929

Of Mice, Dirty Mice, and Men: Using Mice To Understand Human Immunology.
Masopust D, Sivula CP, Jameson SC.
J Immunol. 2017 Jul 15;199(2):383-388. doi: 10.4049/jimmunol.1700453. Review.
PMID: 28696328