The Center for Immunology produces an immense amount of research each year.  The data produced is comprehensive and timely to research across the globe.  Our research is supported by Government, Commercial and Industrial grants and private funds and is produced in our state of the art research facilities.  The research is carried out by faculty members, visiting scholars, post-doctoral fellows, graduate and undergraduate students and technicians. The Center for Immunology also has a strong collaboration history with colleagues at other Universities and research companies worldwide.


 To honor Center for Immunology faculty with 200 or more citations on one paper we have created our wall of honor. 


View the Wall of Honor


2018 publications

T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells.
Beura LK, Wijeyesinghe S, Thompson EA, Macchietto MG, Rosato PC, Pierson MJ, Schenkel JM, Mitchell JS, Vezys V, Fife BT, Shen S, Masopust D.
Immunity. 2018 Feb 20;48(2):327-338.e5. doi: 10.1016/j.immuni.2018.01.015.
PMID: 29466758

Understanding Subset Diversity in T Cell Memory.
Jameson SC, Masopust D.
Immunity. 2018 Feb 20;48(2):214-226. doi: 10.1016/j.immuni.2018.02.010. Review.
PMID: 29466754

Strain Tracking Reveals the Determinants of Bacterial Engraftment in the Human Gut Following Fecal Microbiota Transplantation.
Smillie CS, Sauk J, Gevers D, Friedman J, Sung J, Youngster I, Hohmann EL, Staley C, Khoruts A, Sadowsky MJ, Allegretti JR, Smith MB, Xavier RJ, Alm EJ.
Cell Host Microbe. 2018 Feb 14;23(2):229-240.e5. doi: 10.1016/j.chom.2018.01.003.

Many Th Cell Subsets Have Fas Ligand-Dependent Cytotoxic Potential.
Kotov DI, Kotov JA, Goldberg MF, Jenkins MK.
J Immunol. 2018 Feb 7. pii: ji1700420. doi: 10.4049/jimmunol.1700420. [Epub ahead of print]
PMID: 29436413

CD301b/MGL2+ Mononuclear Phagocytes Orchestrate Autoimmune Cardiac Valve Inflammation and Fibrosis.
Meier LA, Auger JL, Engelson BJ, Cowan HM, Breed ER, Gonzalez-Torres MI, Boyer JD, Verma M, Marath A, Binstadt BA.
Circulation. 2018 Jan 31. pii: CIRCULATIONAHA.117.033144. doi: 10.1161/CIRCULATIONAHA.117.033144. [Epub ahead of print] 
PMID: 29386201

Cutting Edge: Allograft Rejection Is Associated with Weak T Cell Responses to Many Different Graft Leukocyte-Derived Peptides.
Burrack AL, Malhotra D, Dileepan T, Osum KC, Swanson LA, Fife BT, Jenkins MK.
J Immunol. 2018 Jan 15;200(2):477-482. doi: 10.4049/jimmunol.1701434. Epub 2017 Dec 18.
PMID: 29255075

Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory.
Beura LK, Mitchell JS, Thompson EA, Schenkel JM, Mohammed J, Wijeyesinghe S, Fonseca R, Burbach BJ, Hickman HD, Vezys V, Fife BT, Masopust D.
Nat Immunol. 2018 Feb;19(2):173-182. doi: 10.1038/s41590-017-0029-3. Epub 2018 Jan 8.
PMID: 29311694

Do Memory B Cells Form Secondary Germinal Centers? It Depends.
Pape KA, Jenkins MK.
Cold Spring Harb Perspect Biol. 2018 Jan 2;10(1). pii: a029116. doi: 10.1101/cshperspect.a029116. Review.
PMID: 28320756

Functional Genomics of Host-Microbiome Interactions in Humans.
Luca F, Kupfer SS, Knights D, Khoruts A, Blekhman R.
Trends Genet. 2018 Jan;34(1):30-40. doi: 10.1016/j.tig.2017.10.001. Epub 2017 Oct 26. Review.
PMID: 29107345

2017 publications

Is a Human CD8 T-Cell Vaccine Possible, and if So, What Would It Take? CD8 T-Cell Vaccines: To B or Not to B?
Beura LK, Jameson SC, Masopust D.
Cold Spring Harb Perspect Biol. 2017 Dec 18. pii: a028910. doi: 10.1101/cshperspect.a028910. [Epub ahead of print]
PMID: 29254982

T Cell-Mediated Beta Cell Destruction: Autoimmunity and Alloimmunity in the Context of Type 1 Diabetes.
Burrack AL, Martinov T, Fife BT.
Front Endocrinol (Lausanne). 2017 Dec 5;8:343. doi: 10.3389/fendo.2017.00343. eCollection 2017. Review.
PMID: 29259578

Increased Effector Memory Insulin-Specific CD4+T-cells Correlate with Insulin Autoantibodies in Recent-Onset Type 1 Diabetic Patients.
Spanier JA, Sahli NL, Wilson JC, Martinov T, Dileepan T, Burrack AL, Finger EB, Blazar BR, Michels AW, Moran A, Jenkins MK, Fife BT.
Diabetes. 2017 Dec;66(12):3051-3060. doi: 10.2337/db17-0666. Epub 2017 Aug 25
PMID: 28842400

Contemporary Applications of Fecal Microbiota Transplantation to Treat Intestinal Diseases in Humans.
Staley C, Khoruts A, Sadowsky MJ.
Arch Med Res. 2017 Nov 25. pii: S0188-4409(17)30235-7. doi: 10.1016/j.arcmed.2017.11.006. [Epub ahead of print] Review.

Functional Genomics of Host-Microbiome Interactions in Humans.
Luca F, Kupfer SS, Knights D, Khoruts A, Blekhman R.
Trends Genet. 2017 Oct 26. pii: S0168-9525(17)30182-8. doi: 10.1016/j.tig.2017.10.001. [Epub ahead of print] Review.
PMID: 29107345

Induction of vaginal-resident HIV-specific CD8 T cells with mucosal prime-boost immunization.
Tan HX, Wheatley AK, Esterbauer R, Jegaskanda S, Glass JJ, Masopust D, De Rose R, Kent SJ.
Mucosal Immunol. 2017 Oct 25. doi: 10.1038/mi.2017.89. [Epub ahead of print]
PMID: 29067995

Wait, Wait … OK Now Go In: iNKT Cells Resolve Liver Inflammation.
Wang H, Hogquist KA.
Immunity. 2017 Oct 17;47(4):609-610. doi: 10.1016/j.immuni.2017.10.002.
PMID: 29045892

Hemodynamic Forces Sculpt Developing Heart Valves through a KLF2-WNT9B Paracrine Signaling Axis.
Goddard LM, Duchemin AL, Ramalingan H, Wu B, Chen M, Bamezai S, Yang J, Li L, Morley MP, Wang T, Scherrer-Crosbie M, Frank DB, Engleka KA, Jameson SC, Morrisey EE, Carroll TJ, Zhou B, Vermot J, Kahn ML.
Dev Cell. 2017 Oct 13. pii: S1534-5807(17)30782-7. doi: 10.1016/j.devcel.2017.09.023. [Epub ahead of print]
PMID: 29056552

Defining total-body AIDS-virus burden with implications for curative strategies.
Estes JD, Kityo C, Ssali F, Swainson L, Makamdop KN, Del Prete GQ, Deeks SG, Luciw PA, Chipman JG, Beilman GJ, Hoskuldsson T, Khoruts A, Anderson J, Deleage C, Jasurda J, Schmidt TE, Hafertepe M, Callisto SP, Pearson H, Reimann T, Schuster J, Schoephoerster J, Southern P, Perkey K, Shang L, Wietgrefe SW, Fletcher CV, Lifson JD, Douek DC, McCune JM, Haase AT, Schacker TW.
Nat Med. 2017 Oct 2. doi: 10.1038/nm.4411. [Epub ahead of print]
PMID: 28967921

Landscape review of current HIV 'kick and kill' cure research - some kicking, not enough killing.
Thorlund K, Horwitz MS, Fife BT, Lester R, Cameron DW.
BMC Infect Dis. 2017 Aug 29;17(1):595. doi: 10.1186/s12879-017-2683-3. Review.
PMID: 28851294

Directing T cell fate: How thymic antigen presenting cells coordinate thymocyte selection.
Breed ER, Lee ST, Hogquist KA.
Semin Cell Dev Biol. 2017 Aug 9. pii: S1084-9521(16)30452-9. doi: 10.1016/j.semcdb.2017.07.045. [Epub ahead of print] Review.
PMID: 28800929

Of Mice, Dirty Mice, and Men: Using Mice To Understand Human Immunology.
Masopust D, Sivula CP, Jameson SC.
J Immunol. 2017 Jul 15;199(2):383-388. doi: 10.4049/jimmunol.1700453. Review.
PMID: 28696328