The Center for Immunology produces an immense amount of research each year.  The data produced is comprehensive and timely to research across the globe.  Our research is supported by Government, Commercial and Industrial grants and private funds and is produced in our state of the art research facilities.  The research is carried out by faculty members, visiting scholars, post-doctoral fellows, graduate, and undergraduate students and technicians. The Center for Immunology also has a strong collaboration history with colleagues at other Universities and research companies worldwide.


 To honor Center for Immunology faculty with 200 or more citations on one paper we have created our wall of honor. 


View the Wall of Honor


2020 publications

Retrograde migration supplies resident memory T cells to lung-draining LN after influenza infection.
Stolley JM, Johnston TS, Soerens AG, Beura LK, Rosato PC, Joag V, Wijeyesinghe SP, Langlois RA, Osum KC, Mitchell JS, Masopust D.
J Exp Med. 2020 Aug 3;217(8):e20192197. doi: 10.1084/jem.20192197.
PMID: 32568362

Chemotherapy brings virtual memory T cells into reality for cancer therapy.
Schmiechen ZC, Burrack AL, Stromnes IM.
Cell Mol Immunol. 2020 Jul 3. doi: 10.1038/s41423-020-0496-6. Online ahead of print.
PMID: 32620786

The relationship between CD4+ follicular helper T cells and CD8+ resident memory T cells: sisters or distant cousins?
Peng C, Jameson SC.
Int Immunol. 2020 Jul 3:dxaa045. doi: 10.1093/intimm/dxaa045. Online ahead of print.
PMID: 32620009

Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function.
Choi JW, Withers SS, Chang H, Spanier JA, De La Trinidad VL, Panesar H, Fife BT, Sciammas R, Sparger EE, Moore PF, Kent MS, Rebhun RB, McSorley SJ.
PLoS One. 2020 Jul 2;15(7):e0235518. doi: 10.1371/journal.pone.0235518. eCollection 2020.
PMID: 32614928

KLRG1+ Memory CD8 T Cells Combine Properties of Short-Lived Effectors and Long-Lived Memory.
Renkema KR, Huggins MA, Borges da Silva H, Knutson TP, Henzler CM, Hamilton SE.
J Immunol. 2020 Jul 1:ji1901512. doi: 10.4049/jimmunol.1901512. Online ahead of print.
PMID: 32611727

New Insights into the Immune System Using Dirty Mice.
Hamilton SE, Badovinac VP, Beura LK, Pierson M, Jameson SC, Masopust D, Griffith TS.
J Immunol. 2020 Jul 1;205(1):3-11. doi: 10.4049/jimmunol.2000171.
PMID: 32571979

Polymer-mediated delivery of vaccines to treat opioid use disorders and to reduce opioid-induced toxicity.
Gradinati V, Baruffaldi F, Abbaraju S, Laudenbach M, Amin R, Gilger B, Velagaleti P, Pravetoni M.
Vaccine. 2020 Jun 19;38(30):4704-4712. doi: 10.1016/j.vaccine.2020.05.027. Epub 2020 May 19.
PMID: 32439214

Comparative phenotypes of peripheral blood and spleen cells from cancer patients.
Cole KE, Ly QP, Hollingsworth MA, Cox JL, Stromnes IM, Padussis JC, Foster JM, Vargas LM, Talmadge JE.
Int Immunopharmacol. 2020 Jun 7;85:106655. doi: 10.1016/j.intimp.2020.106655. [Epub ahead of print]
PMID: 32521493

Instructing Memory in CD8+ Thymocytes.
Ashby KM, Hogquist KA.
Trends Immunol. 2020 Jun 6. pii: S1471-4906(20)30121-6. doi: 10.1016/ [Epub ahead of print]
PMID: 32518054

Different hierarchies of anti-modified protein autoantibody reactivities in rheumatoid arthritis.
Sahlström P, Hansson M, Steen J, Amara K, Titcombe PJ, Forsström B, Stålesen R, Israelsson L, Piccoli L, Lundberg K, Klareskog L, Mueller DL, Catrina AI, Skriner K, Malmström V, Grönwall C.
Arthritis Rheumatol. 2020 Jun 5. doi: 10.1002/art.41385. Online ahead of print
PMID: 32501655

TLR7/8 Agonist-Loaded Nanoparticles Augment NK Cell-Mediated Antibody-Based Cancer Immunotherapy.
Kim H, Khanna V, Kucaba TA, Zhang W, Sehgal D, Ferguson DM, Griffith TS, Panyam J
Mol Pharm. 2020 Jun 1;17(6):2109-2124. doi: 10.1021/acs.molpharmaceut.0c00271. Epub 2020 May 21.
PMID: 32383885

T Cell Receptor Engineered Lymphocytes for Cancer Therapy.
Rollins MR, Spartz EJ, Stromnes IM.
Curr Protoc Immunol. 2020 Jun;129(1):e97. doi: 10.1002/cpim.97.
PMID: 32432843

Probiotics: promise, evidence, and hope.
Khoruts A, Hoffmann DE, Britton RA.
Gastroenterology. 2020 May 25. pii: S0016-5085(20)34728-4. doi: 10.1053/j.gastro.2020.05.058. [Epub ahead of print] No abstract available. 
PMID: 32531290

Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer.
Witschen PM, Chaffee TS, Brady NJ, Huggins DN, Knutson TP, LaRue RS, Munro SA, Tiegs L, McCarthy JB, Nelson AC, Schwertfeger KL.
Cancers (Basel). 2020 May 22;12(5):E1325. doi: 10.3390/cancers12051325.
PMID: 32455980

The Immune Landscape of Visceral Adipose Tissue During Obesity and Aging.
Khan S, Chan YT, Revelo XS, Winer DA.
Front Endocrinol (Lausanne). 2020 May 15;11:267. doi: 10.3389/fendo.2020.00267. eCollection 2020.
PMID: 32499756

Polymer-mediated delivery of vaccines to treat opioid use disorders and to reduce opioid-induced toxicity.
Gradinati V, Baruffaldi F, Abbaraju S, Laudenbach M, Amin R, Gilger B, Velagaleti P, Pravetoni M.
Vaccine. 2020 May 19:S0264-410X(20)30646-0. doi: 10.1016/j.vaccine.2020.05.027. Online ahead of print.
PMID: 32439214

T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers.
Arunachalam PS, Charles TP, Joag V, Bollimpelli VS, Scott MKD, Wimmers F, Burton SL, Labranche CC, Petitdemange C, Gangadhara S, Styles TM, Quarnstrom CF, Walter KA, Ketas TJ, Legere T, Jagadeesh Reddy PB, Kasturi SP, Tsai A, Yeung BZ, Gupta S, Tomai M, Vasilakos J, Shaw GM, Kang CY, Moore JP, Subramaniam S, Khatri P, Montefiori D, Kozlowski PA, Derdeyn CA, Hunter E, Masopust D, Amara RR, Pulendran B.
Nat Med. 2020 May 11. doi: 10.1038/s41591-020-0858-8. Online ahead of print.
PMID: 32393800

Acquired Resistance to Immune Checkpoint Blockade Therapies.
Zhao X, Wangmo D, Robertson M, Subramanian S.
Cancers (Basel). 2020 May 5;12(5):E1161. doi: 10.3390/cancers12051161.
PMID: 32380703

CD8+ T cells mediate ultraviolet A-induced immunomodulation in a model of extracorporeal photochemotherapy.
Hequet O, Nosbaum A, Guironnet-Paquet A, Blasco E, Nicolas-Virelizier E, Griffith TS, Rigal D, Cognasse F, Nicolas JF, Vocanson M.
Eur J Immunol. 2020 May;50(5):725-735. doi: 10.1002/eji.201948318. Epub 2020 Feb 10.
PMID: 32012249

Antigen discovery unveils resident memory and migratory cell roles in antifungal resistance.
Dobson HE, Dias LDS, Kohn EM, Fites S, Wiesner DL, Dileepan T, Kujoth GC, Abraham A, Ostroff GR, Klein BS, Wüthrich M.
Mucosal Immunol. 2020 May;13(3):518-529. doi: 10.1038/s41385-019-0244-3. Epub 2020 Jan 3.
PMID: 31900406

Single Cell RNA Sequencing in Atherosclerosis Research.
Williams JW, Winkels H, Durant CP, Zaitsev K, Ghosheh Y, Ley K.
Circ Res. 2020 Apr 24;126(9):1112-1126. doi: 10.1161/CIRCRESAHA.119.315940. Epub 2020 Apr 23.
PMID: 32324494

NCOR1 Orchestrates Transcriptional Landscapes and Effector Functions of CD4+ T Cells.
Hainberger D, Stolz V, Zhu C, Schuster M, Müller L, Hamminger P, Rica R, Waltenberger D, Alteneder M, Krausgruber T, Hladik A, Knapp S, Bock C, Trauner M, Farrar MA, Ellmeier W. 
Front Immunol. 2020 Apr 3;11:579. doi: 10.3389/fimmu.2020.00579. eCollection 2020.
PMID: 32318068

Is the opioid use disorder epidemic impacting our immunological health?
Pravetoni M.
Brain Behav Immun. 2020 Apr 10. pii: S0889-1591(20)30487-6. doi: 10.1016/j.bbi.2020.04.022. [Epub ahead of print] No abstract available. 
PMID: 32283290

Exploiting antibody biology for the treatment of cancer.
Khanna V, Panyam J, Griffith TS.
Immunotherapy. 2020 Mar 24. doi: 10.2217/imt-2019-0118. [Epub ahead of print]
PMID:  32208784

Evolutionarily conserved resistance to phagocytosis observed in melanoma cells is insensitive to upregulation of pro-phagocytic signals and to CD47 blockade.
Anderson KL, Snyder KM, Ito D, Lins DC, Mills LJ, Weiskopf K, Ring NG, Ring AM, Shimizu Y, Mescher MF, Weissman IL, Modiano JF.
Melanoma Res. 2020 Apr;30(2):147-158. doi: 10.1097/CMR.0000000000000629.
PMID:  31205227

Gut dysbiosis during antileukemia chemotherapy versus allogeneic hematopoietic cell transplantation.
Rashidi A, Kaiser T, Graiziger C, Holtan SG, Rehman TU, Weisdorf DJ, Dunny GM, Khoruts A, Staley C.
Cancer. 2020 Apr 1;126(7):1434-1447. doi: 10.1002/cncr.32641. Epub 2019 Dec 24.
PMID:  31873965

Developmental plasticity allows outside-in immune responses by resident memory T cells.
Fonseca R, Beura LK, Quarnstrom CF, Ghoneim HE, Fan Y, Zebley CC, Scott MC, Fares-Frederickson NJ, Wijeyesinghe S, Thompson EA, Borges da Silva H, Vezys V, Youngblood B, Masopust D
Nat Immunol. 2020 Apr;21(4):412-421. doi: 10.1038/s41590-020-0607-7. Epub 2020 Feb 17.

Neutrophils Recirculate through Lymph Nodes to Survey Tissues for Pathogens.
Bogoslowski A, Wijeyesinghe S, Lee WY, Chen CS, Alanani S, Jenne C, Steeber DA, Scheiermann C, Butcher EC, Masopust D, Kubes P.
J Immunol. 2020 Mar 23. pii: ji2000022. doi: 10.4049/jimmunol.2000022. [Epub ahead of print]
PMID:  32205425

Impact of Repeated Cycles of EGF Bispecific Angiotoxin (eBAT) Administered at a Reduced Interval from Doxorubicin Chemotherapy in Dogs with Splenic Hemangiosarcoma.
Borgatti A, Fieberg A, Winter AL, Stuebner K, Taras E, Todhunter D, Masyr A, Rendhal A, Vallera DA, Koopmeiners JS, Modiano JF.
Vet Comp Oncol. 2020 Mar 18. doi: 10.1111/vco.12590. [Epub ahead of print]
PMID:  32187827

Recent advances in iNKT cell development.
Hogquist K, Georgiev H.
F1000Res. 2020 Feb 20;9. pii: F1000 Faculty Rev-127. doi: 10.12688/f1000research.21378.1. eCollection 2020. Review.
PMID:  32148771

Blood and tissue biomarker analysis in dogs with osteosarcoma treated with palliative radiation and intra-tumoral autologous natural killer cell transfer.
Judge SJ, Yanagisawa M, Sturgill IR, Bateni SB, Gingrich AA, Foltz JA, Lee DA, Modiano JF, Monjazeb AM, Culp WTN, Rebhun RB, Murphy WJ, Kent MS, Canter RJ.
PLoS One. 2020 Feb 21;15(2):e0224775. doi: 10.1371/journal.pone.0224775. eCollection 2020

Interruption of continuous opioid exposure exacerbates drug-evoked adaptations in the mesolimbic dopamine system.
Lefevre EM, Pisansky MT, Toddes C, Baruffaldi F, Pravetoni M, Tian L, Kono TJY, Rothwell PE.
Neuropsychopharmacology. 2020 Feb 20. doi: 10.1038/s41386-020-0643-x. [Epub ahead of print]

Myocardial B cells are a subset of circulating lymphocytes with delayed transit through the heart.
Adamo L, Rocha-Resende C, Lin CY, Evans S, Williams J, Dun H, Li W, Mpoy C, Andhey PS, Rogers BE, Lavine K, Kreisel D, Artyomov M, Randolph GJ, Mann DL.
JCI Insight. 2020 Feb 13;5(3). pii: 134700. doi: 10.1172/jci.insight.134700.
PMID: 31945014

PD-1+ stemlike CD8 T cells are resident in lymphoid tissues during persistent LCMV infection.
Im SJ, Konieczny BT, Hudson WH, Masopust D, Ahmed R.
Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4292-4299. doi: 10.1073/pnas.1917298117.
PMID: 32034098

Integrating resident memory into T cell differentiation models.
Rosato PC, Wijeyesinghe S, Stolley JM, Masopust D.
Curr Opin Immunol. 2020 Feb 1;63:35-42. doi: 10.1016/j.coi.2020.01.001. [Epub ahead of print] Review.
PMID: 32018169

Interactions between the gut microbiome and host gene regulation in cystic fibrosis.
Dayama G, Priya S, Niccum DE, Khoruts A, Blekhman R.
Genome Med. 2020 Jan 28;12(1):12. doi: 10.1186/s13073-020-0710-2.
PMID: 31992345

VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance.
ElTanbouly MA, Zhao Y, Nowak E, Li J, Schaafsma E, Le Mercier I, Ceeraz S, Lines JL, Peng C, Carriere C, Huang X, Day M, Koehn B, Lee SW, Silva Morales M, Hogquist KA, Jameson SC, Mueller D, Rothstein J, Blazar BR, Cheng C, Noelle RJ.
Science. 2020 Jan 17;367(6475). pii: eaay0524. doi: 10.1126/science.aay0524.
PMID: 31949051

Vitamin D3-mediated resistance to a multiple sclerosis model disease depends on myeloid cell 1,25-dihydroxyvitamin D3 synthesis and correlates with increased CD4+ T cell CTLA-4 expression.
Spanier JA, Nashold FE, Nelson CD, Praska CE, Hayes CE.
J Neuroimmunol. 2020 Jan 15;338:577105. doi: 10.1016/j.jneuroim.2019.577105. Epub 2019 Nov 7.
PMID: 31731231



2019 publications

2018 publications


2017 publications