The Center for Immunology produces an immense amount of research each year.  The data produced is comprehensive and timely to research across the globe.  Our research is supported by Government, Commercial and Industrial grants and private funds and is produced in our state of the art research facilities.  The research is carried out by faculty members, visiting scholars, post-doctoral fellows, graduate and undergraduate students and technicians. The Center for Immunology also has a strong collaboration history with colleagues at other Universities and research companies worldwide.


 To honor Center for Immunology faculty with 200 or more citations on one paper we have created our wall of honor. 


View the Wall of Honor


2017 publications

Role of bone marrow-derived CD11c+ dendritic cells in systolic overload-induced left ventricular inflammation, fibrosis and hypertrophy.
Wang H, Kwak D, Fassett J, Liu X, Yao W, Weng X, Xu X, Xu Y, Bache RJ, Mueller DL, Chen Y.
Basic Res Cardiol. 2017 May;112(3):25. doi: 10.1007/s00395-017-0615-4. Epub 2017 Mar 27.
PMID: 28349258

Cytokine-mediated activation of human ex vivo-expanded Vγ9Vδ2 T cells.
Domae E, Hirai Y, Ikeo T, Goda S, Shimizu Y.
Oncotarget. 2017 Apr 28. doi: 10.18632/oncotarget.17498. [Epub ahead of print]

Synthesis and Biological Evaluation of Bile Acid Analogues Inhibitory to Clostridium difficile Spore Germination.
Stoltz KL, Erickson R, Staley C, Weingarden AR, Romens E, Steer CJ, Khoruts A, Sadowsky MJ, Dosa PI.
J Med Chem. 2017 Apr 27;60(8):3451-3471. doi: 10.1021/acs.jmedchem.7b00295. Epub 2017 Apr 12.
PMID: 28402634

Fecal Microbiota Transplantation - Early Steps on a Long Journey Ahead.
Khoruts A.
Gut Microbes. 2017 Apr 10:0. doi: 10.1080/19490976.2017.1316447. [Epub ahead of print] No abstract available.
PMID: 28394706

Role of bone marrow-derived CD11c+ dendritic cells in systolic overload-induced left ventricular inflammation, fibrosis and hypertrophy.
Wang H, Kwak D, Fassett J, Liu X, Yao W, Weng X, Xu X, Xu Y, Bache RJ, Mueller DL, Chen Y.
Basic Res Cardiol. 2017 May;112(3):25. doi: 10.1007/s00395-017-0615-4. Epub 2017 Mar 27.
PMID: 28349258

Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival.
Katerndahl CD, Heltemes-Harris LM, Willette MJ, Henzler CM, Frietze S, Yang R, Schjerven H, Silverstein KA, Ramsey LB, Hubbard G, Wells AD, Kuiper RP, Scheijen B, van Leeuwen FN, Müschen M, Kornblau SM, Farrar MA.
Nat Immunol. 2017 Apr 3. doi: 10.1038/ni.3716. [Epub ahead of print]
PMID: 28369050

Relationship between CD4 Regulatory T Cells and Anergy In Vivo.
Kalekar LA, Mueller DL.
J Immunol. 2017 Apr 1;198(7):2527-2533. doi: 10.4049/jimmunol.1602031. Review.
PMID: 28320913

Tissue-resident memory T cells live off the fat of the land.
Stolley JM, Masopust D.
Cell Res. 2017 Mar 31. doi: 10.1038/cr.2017.49. [Epub ahead of print]
PMID: 28361896

What Is the Predictive Value of Animal Models for Vaccine Efficacy in Humans? Reevaluating the Potential of Mouse Models for the Human Immune System.
Jameson SC, Masopust D.
Cold Spring Harb Perspect Biol. 2017 Mar 27. pii: a029132. doi: 10.1101/cshperspect.a029132. [Epub ahead of print]
PMID: 28348039

Do Memory B Cells Form Secondary Germinal Centers? It Depends.
Pape KA, Jenkins MK.
Cold Spring Harb Perspect Biol. 2017 Mar 20. pii: a029116. doi: 10.1101/cshperspect.a029116. [Epub ahead of print]
PMID: 28320756

Tissue resident memory T cells and viral immunity.
Rosato PC, Beura LK, Masopust D.
Curr Opin Virol. 2017 Feb;22:44-50. doi: 10.1016/j.coviro.2016.11.011. Epub 2016 Dec 14. Review.
PMID: 27987416

Successful Resolution of Recurrent Clostridium difficile Infection using Freeze-Dried, Encapsulated Fecal Microbiota; Pragmatic Cohort Study.
Staley C, Hamilton MJ, Vaughn BP, Graiziger CT, Newman KM, Kabage AJ, Sadowsky MJ, Khoruts A.
Am J Gastroenterol. 2017 Feb 14. doi: 10.1038/ajg.2017.6. [Epub ahead of print]
PMID: 28195180

Different Lymphocyte Populations Direct Dichotomous Eosinophil or Neutrophil Responses to Pulmonary Cryptococcus Infection.
Wiesner DL, Smith KD, Kashem SW, Bohjanen PR, Nielsen K.
J Immunol. 2017 Feb 15;198(4):1627-1637. doi: 10.4049/jimmunol.1600821. 
PMID: 28069805

Antigen-Presenting Cells in the Skin.
Kashem SW, Haniffa M, Kaplan DH.
Annu Rev Immunol. 2017 Feb 6. doi: 10.1146/annurev-immunol-051116-052215. [Epub ahead of print]
PMID: 28226228

Repeated hapten exposure induces persistent tactile sensitivity in mice modeling localized provoked vulvodynia.
Landry J, Martinov T, Mengistu H, Dhanwada J, Benck CJ, Kline J, Boo B, Swanson L, Tonc E, Daughters R, Fife BT, Chatterjea D.
PLoS One. 2017 Feb 3;12(2):e0169672. doi: 10.1371/journal.pone.0169672.
PMID: 28158195

Gut-sparing treatment of urinary tract infection in patients at high risk of Clostridium difficile infection.
Staley C, Vaughn BP, Graiziger CT, Sadowsky MJ, Khoruts A.
J Antimicrob Chemother2017 Feb;72(2):522-528. doi: 10.1093/jac/dkw499. 
PMID: 27999027

Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study.
Kang DW, Adams JB, Gregory AC, Borody T, Chittick L, Fasano A, Khoruts A, Geis E, Maldonado J, McDonough-Means S, Pollard EL, Roux S, Sadowsky MJ, Lipson KS, Sullivan MB, Caporaso JG, Krajmalnik-Brown R.
Microbiome. 2017 Jan 23;5(1):10. doi: 10.1186/s40168-016-0225-7.
PMID: 28122648

Treatment of recurrent Clostridium difficile infection using fecal microbiota transplantation in patients with inflammatory bowel disease.
Newman KM, Rank KM, Vaughn BP, Khoruts A.
Gut Microbes. 2017 Jan 19:0. doi: 10.1080/19490976.2017.1279377. [Epub ahead of print]
PMID: 28102756

Cutting Edge: Adenosine A2a Receptor Signals Inhibit Germinal Center T Follicular Helper Cell Differentiation during the Primary Response to Vaccination.
Schmiel SE, Yang JA, Jenkins MK, Mueller DL.
J Immunol. 2017 Jan 15;198(2):623-628. doi: 10.4049/jimmunol.1601686.
PMID: 27986907

STAT5 and CD4 + T Cell Immunity.
Owen DL, Farrar MA.
F1000Res. 2017 Jan 11;6:32. doi: 10.12688/f1000research.9838.1. Review.

Identification of MHC-Bound Peptides from Dendritic Cells Infected with Salmonella enterica Strain SL1344: Implications for a Nontyphoidal Salmonella Vaccine.
Karunakaran KP, Yu H, Jiang X, Chan Q, Goldberg MF, Jenkins MK, Foster LJ, Brunham RC.
J Proteome Res. 2017 Jan 6;16(1):298-306. doi: 10.1021/acs.jproteome.6b00926.
PMID: 27802388

Sleeve Gastrectomy Drives Persistent Shifts in the Gut Microbiome.
Jahansouz C, Staley C, Bernlohr DA, Sadowsky MJ, Khoruts A, Ikramuddin S.
Surg Obes Relat Dis. 2017 Jan 4. pii: S1550-7289(17)30003-5. doi: 10.1016/j.soard.2017.01.003. [Epub ahead of print]
PMID: 28279578

Analysis of gut microbiota - An ever changing landscape.
Sadowsky MJ, Staley C, Heiner C, Hall R, Kelly CR, Brandt L, Khoruts A.
Gut Microbes. 2017 Jan 4:1-8. doi: 10.1080/19490976.2016.1277313. [Epub ahead of print]
PMID: 28051919

Toward revision of antimicrobial therapies in hematopoietic stem cell transplantation: target the pathogens, but protect the indigenous microbiota.
Khoruts A, Hippen KL, Lemire AM, Holtan SG, Knights D, Young JH.
Transl Res. 2017 Jan;179:116-125. doi: 10.1016/j.trsl.2016.07.013. Review.
PMID: 27513211

Interaction of gut microbiota with bile acid metabolism and its influence on disease states.
Staley C, Weingarden AR, Khoruts A, Sadowsky MJ.
Appl Microbiol Biotechnol. 2017 Jan;101(1):47-64. doi: 10.1007/s00253-016-8006-6. Review.
PMID: 27888332

Gene Expression Profiling in Blood and Affected Muscle Tissues Reveals Differential Activation Pathways in Patients with New-onset Juvenile and Adult Dermatomyositis.
López De Padilla CM, Crowson CS, Hein MS, Pendegraft RS, Strausbauch MA, Niewold TB, Ernste FC, Peterson E, Baechler EC, Reed AM.
J Rheumatol. 2017 Jan;44(1):117-124. doi: 10.3899/jrheum.160293.
PMID: 27803134