2018 Publications


2018 Publications

Breaking through to the Other Side: Microenvironment Contributions to DCIS Initiation and Progression.
Nelson AC, Machado HL, Schwertfeger KL.
J Mammary Gland Biol Neoplasia. 2018 Dec;23(4):207-221. doi: 10.1007/s10911-018-9409-z. Epub 2018 Aug 31. Review.
PMID:30168075

Salmonella Persist in Activated Macrophages in T Cell-Sparse Granulomas but Are Contained by Surrounding CXCR3 Ligand-Positioned Th1 Cells.
Goldberg MF, Roeske EK, Ward LN, Pengo T, Dileepan T, Kotov DI, Jenkins MK.
Immunity. 2018 Dec 18;49(6):1090-1102.e7. doi: 10.1016/j.immuni.2018.10.009. Epub 2018 Dec 11.
PMID: 30552021

Anergy into T regulatory cells: an integration of metabolic cues and epigenetic changes at the Foxp3 conserved non-coding sequence 2.
Silva Morales M, Mueller D.
F1000Res. 2018 Dec 17;7. pii: F1000 Faculty Rev-1938. doi: 10.12688/f1000research.16551.1. eCollection 2018. Review.
PMID:30613389

Cutting Edge: T Cell-Dependent Plasmablasts Form in the Absence of Single Differentiated CD4+ T Cell Subsets.
Kotov JA, Jenkins MK.
J Immunol. 2018 Dec 14. pii: ji1801349. doi: 10.4049/jimmunol.1801349. [Epub ahead of print]
PMID: 30552165

Engineered Small-Molecule Control of Influenza A Virus Replication.
Fay EJ, Aron SL, Stone IA, Waring BM, Plemper RK, Langlois RA.
J Virol. 2018 Dec 10;93(1). pii: e01677-18. doi: 10.1128/JVI.01677-18. Print 2019 Jan 1.
PMID: 30282710

Adenosine 2a receptor signals block autoimmune arthritis by inhibiting pathogenic germinal center T follicular helper cells.
Schmiel SE, Kalekar LA, Zhang N, Blankespoor TW, Robinson LJ, Mueller DL.
Arthritis Rheumatol. 2018 Dec 5. doi: 10.1002/art.40796. [Epub ahead of print]
PMID: 30516351

Chrysalis: A New Method for High-Throughput Histo-Cytometry Analysis of Images and Movies.
Kotov DI, Pengo T, Mitchell JS, Gastinger MJ, Jenkins MK.
J Immunol. 2018 Dec 3. pii: ji1801202. doi: 10.4049/jimmunol.1801202. [Epub ahead of print]
PMID:30510065

Directing T cell fate: How thymic antigen presenting cells coordinate thymocyte selection.
Breed ER, Lee ST, Hogquist KA.
Semin Cell Dev Biol. 2018 Dec;84:2-10. doi: 10.1016/j.semcdb.2017.07.045. Epub 2017 Aug 9. Review.
PMID:28800929

Taxol Induces Brk-dependent Prosurvival Phenotypes in TNBC Cells through an AhR/GR/HIF-driven Signaling Axis.
Regan Anderson TM, Ma S, Perez Kerkvliet C, Peng Y, Helle TM, Krutilina RI, Raj GV, Cidlowski JA, Ostrander JH, Schwertfeger KL, Seagroves TN, Lange CA.
Mol Cancer Res. 2018 Nov;16(11):1761-1772. doi: 10.1158/1541-7786.MCR-18-0410. Epub 2018 Jul 10.
PMID:29991529

Acidic pH-responsive polymer nanoparticles as a TLR7/8 agonist delivery platform for cancer immunotherapy.
Kim H, Sehgal D, Kucaba TA, Ferguson DM, Griffith TS, Panyam J.
Nanoscale. 2018 Nov 15;10(44):20851-20862. doi: 10.1039/c8nr07201a.
PMID: 30403212

US Immigration Westernizes the Human Gut Microbiome.
Vangay P, Johnson AJ, Ward TL, Al-Ghalith GA, Shields-Cutler RR, Hillmann BM, Lucas SK, Beura LK, Thompson EA, Till LM, Batres R, Paw B, Pergament SL, Saenyakul P, Xiong M, Kim AD, Kim G, Masopust D, Martens EC, Angkurawaranon C, McGready R, Kashyap PC, Culhane-Pera KA, Knights D.
Cell. 2018 Nov 1;175(4):962-972.e10. doi: 10.1016/j.cell.2018.10.029.
PMID: 30388453

Polymicrobial Sepsis Chronic Immunoparalysis Is Defined by Diminished Ag-Specific T Cell-Dependent B Cell Responses.
Sjaastad FV, Condotta SA, Kotov JA, Pape KA, Dail C, Danahy DB, Kucaba TA, Tygrett LT, Murphy KA, Cabrera-Perez J, Waldschmidt TJ, Badovinac VP, Griffith TS.
Front Immunol. 2018 Oct 31;9:2532. doi: 10.3389/fimmu.2018.02532. eCollection 2018.
PMID: 30429857

Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infections.
Jensen IJ, Winborn CS, Fosdick MG, Shao P, Tremblay MM, Shan Q, Tripathy SK, Snyder CM, Xue HH, Griffith TS, Houtman JC, Badovinac VP.
PLoS Pathog. 2018 Oct 31;14(10):e1007405. doi: 10.1371/journal.ppat.1007405. eCollection 2018 Oct.
PMID: 30379932

Targeting the microbiome: from probiotics to fecal microbiota transplantation.
Khoruts A.
Genome Med. 2018 Oct 30;10(1):80. doi: 10.1186/s13073-018-0592-8.
PMID: 30376869

Enrichment and Quantification of Epitope-specific CD4+ T Lymphocytes using Ferromagnetic Iron-gold and Nickel Nanowires.
Shore DE, Dileepan T, Modiano JF, Jenkins MK, Stadler BJH.
Sci Rep. 2018 Oct 24;8(1):15696. doi: 10.1038/s41598-018-33910-0.
PMID: 30356071

Sleeping Beauty Screen Identifies RREB1 and Other Genetic Drivers in Human B-cell Lymphoma.
Rahrmann EP, Wolf NK, Otto GM, Heltemes Harris L, Ramsey LB, Shu J, LaRue RS, Linden MA, Rathe SK, Starr TK, Farrar MA, Moriarity BS, Largaespada DA.
Mol Cancer Res. 2018 Oct 24. pii: molcanres.0582.2018. doi: 10.1158/1541-7786.MCR-18-0582. [Epub ahead of print]
PMID: 30355676

MicroRNA-Attenuated Virus Vaccines.
Fay EJ, Langlois RA.
Noncoding RNA. 2018 Oct 2;4(4). pii: E25. doi: 10.3390/ncrna4040025. Review.
PMID: 30279330

Cutting Edge: Elevated Leptin during Diet-Induced Obesity Reduces the Efficacy of Tumor Immunotherapy.
Murphy KA, James BR, Sjaastad FV, Kucaba TA, Kim H, Brincks EL, Chua SC Jr, Wilber A, Griffith TS.
J Immunol. 2018 Oct 1;201(7):1837-1841. doi: 10.4049/jimmunol.1701738. Epub 2018 Aug 22.
PMID: 30135180

The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease.
McDonald-Hyman C, Muller JT, Loschi M, Thangavelu G, Saha A, Kumari S, Reichenbach DK, Smith MJ, Zhang G, Koehn BH, Lin J, Mitchell JS, Fife BT, Panoskaltsis-Mortari A, Feser CJ, Kirchmeier AK, Osborn MJ, Hippen KL, Kelekar A, Serody JS, Turka LA, Munn DH, Chi H, Neubert TA, Dustin ML, Blazar BR.
J Clin Invest. 2018 Oct 1;128(10):4604-4621. doi: 10.1172/JCI95713. Epub 2018 Aug 14.
PMID: 30106752

Embracing microbial exposure in mouse research.
Huggins MA, Jameson SC, Hamilton SE.
J Leukoc Biol. 2018 Sep 27. doi: 10.1002/JLB.4RI0718-273R. [Epub ahead of print] Review.
PMID:30260516

1,25-Dihydroxyvitamin D3 increases the methionine cycle, CD4+ T cell DNA methylation and Helios+Foxp3+ T regulatory cells to reverse autoimmune neurodegenerative disease.
Moore JR, Hubler SL, Nelson CD, Nashold FE, Spanier JA, Hayes CE.
J Neuroimmunol. 2018 Nov 15;324:100-114. doi: 10.1016/j.jneuroim.2018.09.008. Epub 2018 Sep 21
PMID:30267995

Distinct antiviral signatures revealed by the magnitude and round of influenza virus replication in vivo.
Sjaastad LE, Fay EJ, Fiege JK, Macchietto MG, Stone IA, Markman MW, Shen S, Langlois RA.
Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):9610-9615. doi: 10.1073/pnas.1807516115. Epub 2018 Sep 4.
PMID: 30181264

Is a Human CD8 T-Cell Vaccine Possible, and if So, What Would It Take? CD8 T-Cell Vaccines: To B or Not to B?
Beura LK, Jameson SC, Masopust D.
Cold Spring Harb Perspect Biol. 2018 Sep 4;10(9). pii: a028910. doi: 10.1101/cshperspect.a028910. Review.
PMID: 29254982

Human plasma cell derived monoclonal antibodies to post-translationally modified proteins recognize amino acid motifs rather than specific proteins.
Steen J, Forsström B, Sahlström P, Odowd V, Israelsson L, Krishnamurthy A, Badreh S, Mathsson Alm L, Compson J, Ramsköld D, Ndlovu W, Rapecki S, Hansson M, Titcombe PJ, Bang H, Mueller DL, Catrina AI, Grönwall C, Skriner K, Nilsson P, Lightwood D, Klareskog L, Malmström V.
Arthritis Rheumatol. 2018 Aug 27. doi: 10.1002/art.40699. [Epub ahead of print]
PMID: 30152202

CCR7 defines a precursor for murine iNKT cells in thymus and periphery.
Wang H, Hogquist KA.
Elife. 2018 Aug 13;7. pii: e34793. doi: 10.7554/eLife.34793.
PMID: 30102153

Fecal Microbiota Transplantation: Current Status in Treatment of GI and Liver Disease.
Vaughn BP, Rank KM, Khoruts A.
Clin Gastroenterol Hepatol. 2018 Jul 25. pii: S1542-3565(18)30751-1. doi: 10.1016/j.cgh.2018.07.026. [Epub ahead of print] Review.
PMID:30055267

Eradication of Established Tumors by Chemically Self-Assembled Nanoring Labeled T Cells.
Petersburg JR, Shen J, Csizmar CM, Murphy KA, Spanier J, Gabrielse K, Griffith TS, Fife B, Wagner CR
ACS Nano. 2018 Jul 24;12(7):6563-6576. doi: 10.1021/acsnano.8b01308. Epub 2018 Jun 4.
PMID: 29792808

A bivalent compound targeting CCR5 and the mu opioid receptor treats inflammatory arthritis pain in mice without inducing pharmacologic tolerance.
Dutta R, Lunzer MM, Auger JL, Akgün E, Portoghese PS, Binstadt BA.
Arthritis Res Ther. 2018 Jul 27;20(1):154. doi: 10.1186/s13075-018-1661-5.
PMID:30053832

Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development.
Miller CN, Proekt I, von Moltke J, Wells KL, Rajpurkar AR, Wang H, Rattay K, Khan IS, Metzger TC, Pollack JL, Fries AC, Lwin WW, Wigton EJ, Parent AV, Kyewski B, Erle DJ, Hogquist KA, Steinmetz LM, Locksley RM, Anderson MS.
Nature. 2018 Jul 18. doi: 10.1038/s41586-018-0345-2. [Epub ahead of print]
PMID:30022164

Cutting Edge: Evidence for Nonvascular Route of Visceral Organ Immunosurveillance by T Cells.
Steinert EM, Thompson EA, Beura LK, Adam OA, Mitchell JS, Guo M, Breed ER, Sjaastad FV, Vezys V, Masopust D.
J Immunol. 2018 Jul 15;201(2):337-342. doi: 10.4049/jimmunol.1800279. Epub 2018 Jun 6.
PMID:29875151

The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8+ T cells.
Borges da Silva H, Beura LK, Wang H, Hanse EA, Gore R, Scott MC, Walsh DA, Block KE, Fonseca R, Yan Y, Hippen KL, Blazar BR, Masopust D, Kelekar A, Vulchanova L, Hogquist KA, Jameson SC.
Nature. 2018 Jul 4. doi: 10.1038/s41586-018-0282-0. [Epub ahead of print]
PMID: 29973721

SETD2 Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma.
Sakthikumar S, Elvers I, Kim J, Arendt ML, Thomas R, Turner-Maier J, Swofford R, Johnson J, Schumacher SE, Alföldi J, Axelsson E, Couto CG, Kisseberth WC, Pettersson ME, Getz G, Meadows JRS, Modiano JF, Breen M, Kierczak M, Forsberg-Nilsson K, Marinescu VD, Lindblad-Toh K.
Cancer Res. 2018 Jul 1;78(13):3421-3431. doi: 10.1158/0008-5472.CAN-17-3558. Epub 2018 May 3.
PMID: 29724721

For T Cells, the Child Is Father of the Man.
Hogquist KA, Hamilton SE.
Cell. 2018 Jun 28;174(1):16-18. doi: 10.1016/j.cell.2018.06.015.
PMID: 29958105

How Lipid-Specific T Cells Become Effectors: The Differentiation of iNKT Subsets.
Wang H, Hogquist KA.
Front Immunol. 2018 Jun 26;9:1450. doi: 10.3389/fimmu.2018.01450. eCollection 2018. Review.
PMID: 29997620

The virtuous self-tolerance of virtual memory T cells.
Truckenbrod EN, Jameson SC.
EMBO J. 2018 Jun 26. pii: e99883. doi: 10.15252/embj.201899883. [Epub ahead of print] No abstract available.
PMID:29946017

Pathogenic citrulline-multispecific B cell receptor clades in rheumatoid arthritis.
Titcombe PJ, Wigerblade G, Sippl N, Zhang N, Shmagel AK, Sahlström P, Zhang Y, Barsness LO, Ghodke-Puranik Y, Baharpoor A, Hansson M, Israelsson L, Skriner K, Niewold TB, Klareskog L, Svensson CI, Amara K, Malmström V, Mueller DL.
Arthritis Rheumatol. 2018 Jun 21. doi: 10.1002/art.40590. [Epub ahead of print]
PMID:29927106

Colorectal cancer mutational profiles correlate with defined microbial communities in the tumor microenvironment.
Burns MB, Montassier E, Abrahante J, Priya S, Niccum DE, Khoruts A, Starr TK, Knights D, Blekhman R.
PLoS Genet. 2018 Jun 20;14(6):e1007376. doi: 10.1371/journal.pgen.1007376. [Epub ahead of print]
PMID:29924794 

Naive B Cells with High-Avidity Germline-Encoded Antigen Receptors Produce Persistent IgM+ and Transient IgG+ Memory B Cells.
Pape KA, Maul RW, Dileepan T, Paustian AS, Gearhart PJ, Jenkins MK.
Immunity. 2018 Jun 19;48(6):1135-1143.e4. doi: 10.1016/j.immuni.2018.04.019. Epub 2018 Jun 5.
PMID:29884459

CD301b/MGL2+ Mononuclear Phagocytes Orchestrate Autoimmune Cardiac Valve Inflammation and Fibrosis.
Meier LA, Auger JL, Engelson BJ, Cowan HM, Breed ER, Gonzalez-Torres MI, Boyer JD, Verma M, Marath A, Binstadt BA.
Circulation. 2018 Jun 5;137(23):2478-2493. doi: 10.1161/CIRCULATIONAHA.117.033144. Epub 2018 Jan 31.
PMID:29386201

Identification and characterization of HIV-specific resident memory CD8+ T cells in human lymphoid tissue.
Buggert M, Nguyen S, Salgado-Montes de Oca G, Bengsch B, Darko S, Ransier A, Roberts ER, Del Alcazar D, Brody IB, Vella LA, Beura L, Wijeyesinghe S, Herati RS, Del Rio Estrada PM, Ablanedo-Terrazas Y, Kuri-Cervantes L, Sada Japp A, Manne S, Vartanian S, Huffman A, Sandberg JK, Gostick E, Nadolski G, Silvestri G, Canaday DH, Price DA, Petrovas C, Su LF, Vahedi G, Dori Y, Frank I, Itkin MG, Wherry EJ, Deeks SG, Naji A, Reyes-Terán G, Masopust D, Douek DC, Betts MR.
Sci Immunol. 2018 Jun 1;3(24). pii: eaar4526. doi: 10.1126/sciimmunol.aar4526.
PMID:29858286

Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes.
Osum KC, Burrack AL, Martinov T, Sahli NL, Mitchell JS, Tucker CG, Pauken KE, Papas K, Appakalai B, Spanier JA, Fife BT.
Sci Rep. 2018 May 29;8(1):8295. doi: 10.1038/s41598-018-26471-9.
PMID:29844327

Induction of vaginal-resident HIV-specific CD8 T cells with mucosal prime-boost immunization.
Tan HX, Wheatley AK, Esterbauer R, Jegaskanda S, Glass JJ, Masopust D, De Rose R, Kent SJ.
Mucosal Immunol. 2018 May;11(3):994-1007. doi: 10.1038/mi.2017.89. Epub 2017 Oct 25.
PMID:29067995

Polymeric nanoparticles encapsulating novel TLR7/8 agonists as immunostimulatory adjuvants for enhanced cancer immunotherapy.
Kim H, Niu L, Larson P, Kucaba TA, Murphy KA, James BR, Ferguson DM, Griffith TS, Panyam J.
Biomaterials. 2018 May;164:38-53. doi: 10.1016/j.biomaterials.2018.02.034. Epub 2018 Feb 17.
PMID: 29482062

Identification of Cellular Sources of IL-2 Needed for Regulatory T Cell Development and Homeostasis.
Owen DL, Mahmud SA, Vang KB, Kelly RM, Blazar BR, Smith KA, Farrar MA.
J Immunol. 2018 May 4. pii: ji1800097. doi: 10.4049/jimmunol.1800097. [Epub ahead of print]
PMID:29728511

Duration of high-dose aspirin therapy does not affect long-term coronary artery outcomes in Kawasaki disease.
Migally K, Braunlin EA, Zhang L, Binstadt BA.
Pediatr Res. 2018 May 2. doi: 10.1038/pr.2018.44. [Epub ahead of print]
PMID:29554081

Is fecal microbiota transplantation a temporary patch for treatment of Clostridium difficile infection or a new frontier of therapeutics?
Khoruts A.
Expert Rev Gastroenterol Hepatol. 2018 May;12(5):435-438. doi: 10.1080/17474124.2018.1465818. Epub 2018 Apr 20.No abstract available.
PMID:29667436

Opioid Dose- and Route-Dependent Efficacy of Oxycodone and Heroin Vaccines in Rats.
Raleigh MD, Laudenbach M, Baruffaldi F, Peterson SJ, Roslawski MJ, Birnbaum AK, Carroll FI, Runyon SP, Winston S, Pentel PR, Pravetoni M.
J Pharmacol Exp Ther. 2018 May;365(2):346-353. doi: 10.1124/jpet.117.247049. Epub 2018 Mar 13.
PMID:29535156

The Contribution of Autoantibodies to Inflammatory Cardiovascular Pathology.
Meier LA, Binstadt BA.
Front Immunol. 2018 Apr 27;9:911. doi: 10.3389/fimmu.2018.00911. eCollection 2018. Review.
PMID: 29755478

Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset.
Hülsdünker J, Ottmüller KJ, Neeff HP, Koyama M, Gao Z, Thomas OS, Follo M, Al-Ahmad A, Prinz G, Duquesne S, Dierbach H, Kirschnek S, Lämmermann T, Blaser MJ, Fife BT, Blazar BR, Beilhack A, Hill GR, Häcker G, Zeiser R.
Blood. 2018 Apr 19;131(16):1858-1869. doi: 10.1182/blood-2017-10-812891. Epub 2018 Feb 20.
PMID:29463561

Blocking interleukin-4 enhances efficacy of vaccines for treatment of opioid abuse and prevention of opioid overdose.
Laudenbach M, Baruffaldi F, Robinson C, Carter P, Seelig D, Baehr C, Pravetoni M.
Sci Rep. 2018 Apr 3;8(1):5508. doi: 10.1038/s41598-018-23777-6.
PMID:29615715 

What Is the Predictive Value of Animal Models for Vaccine Efficacy in Humans? Reevaluating the Potential of Mouse Models for the Human Immune System.
Jameson SC, Masopust D.
Cold Spring Harb Perspect Biol. 2018 Apr 2;10(4). pii: a029132. doi: 10.1101/cshperspect.a029132. Review.
PMID:28348039

Regulatory CD4+ T Cells Recognize MHC-II-Restricted Peptide Epitopes of Apolipoprotein B.
Kimura T, Kobiyama K, Winkels H, Tse K, Miller J, Vassallo M, Wolf D, Ryden C, Orecchioni M, Dileepan T, Jenkins MK, James EA, Kwok WW, Hanna DB, Kaplan RC, Strickler HD, Durkin HG, Kassaye SG, Karim R, Tien PC, Landay AL, Gange SJ, Sidney J, Sette A, Ley K.
Circulation. 2018 Mar 27. pii: CIRCULATIONAHA.117.031420. doi: 10.1161/CIRCULATIONAHA.117.031420. [Epub ahead of print]
PMID:29588316

Interleukin-15 Complex Treatment Protects Mice from Cerebral Malaria by Inducing Interleukin-10-Producing Natural Killer Cells.
Burrack KS, Huggins MA, Taras E, Dougherty P, Henzler CM, Yang R, Alter S, Jeng EK, Wong HC, Felices M, Cichocki F, Miller JS, Hart GT, Johnson AJ, Jameson SC, Hamilton SE.
Immunity. 2018 Mar 20. pii: S1074-7613(18)30088-8. doi: 10.1016/j.immuni.2018.03.012. [Epub ahead of print]
PMID:29625893

Modulation of fatty acid metabolism and immune suppression are features of in vitro tumour sphere formation in ontogenetically distinct dog cancers.
Kim JH, Frantz AM, Sarver AL, Gorden Klukas BH, Lewellen M, O'Brien TD, Dickerson EB, Modiano JF.
Vet Comp Oncol. 2018 Mar;16(1):E176-E184. doi: 10.1111/vco.12368. Epub 2017 Nov 20. Erratum in: Vet Comp Oncol. 2018 Sep;16(3):416.
PMID: 29152836

Many Th Cell Subsets Have Fas Ligand-Dependent Cytotoxic Potential.
Kotov DI, Kotov JA, Goldberg MF, Jenkins MK.
J Immunol. 2018 Mar 15;200(6):2004-2012. doi: 10.4049/jimmunol.1700420. Epub 2018 Feb 7.
PMID:29436413

Inflammatory arthritis in pediatric patients with morphea.
Kashem SW, Correll CK, Vehe RK, Hobday PM, Binstadt BA, Maguiness SM.
J Am Acad Dermatol. 2018 Mar 10. pii: S0190-9622(18)30365-7. doi: 10.1016/j.jaad.2018.03.005. [Epub ahead of print]
PMID:29535035

Antibiotic-induced Disruption of Intestinal Microbiota Contributes to Failure of Vertical Sleeve Gastrectomy.
Jahansouz C, Staley C, Kizy S, Xu H, Hertzel AV, Coryell J, Singroy S, Hamilton M, DuRand M, Bernlohr DA, Sadowsky MJ, Khoruts A, Ikramuddin S.
Ann Surg. 2018 Mar 8. doi: 10.1097/SLA.0000000000002729. [Epub ahead of print]
PMID:29521742

Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: implications for B-cell selection.
Lloyd KA, Steen J, Amara K, Titcombe PJ, Israelsson L, Lundström SL, Zhou D, Zubarev RA, Reed E, Piccoli L, Gabay C, Lanzavecchia A, Baeten D, Lundberg K, Mueller DL, Klareskog L, Malmström V, Grönwall C.
Eur J Immunol. 2018 Mar 7. doi: 10.1002/eji.201747446. [Epub ahead of print]
PMID: 29512823

Intravenous Labeling and Analysis of the Content of Thymic Perivascular Spaces.
Ruscher R, Hogquist KA.
Bio Protoc. 2018 Mar 5;8(5). pii: e2757. doi: 10.21769/bioprotoc.2757.
PMID: 29644257

RelB-Deficient Dendritic Cells Promote the Development of Spontaneous Allergic Airway Inflammation.
Nair PM, Starkey MR, Haw TJ, Ruscher R, Liu G, Maradana MR, Thomas R, O'Sullivan BJ, Hansbro PM.
Am J Respir Cell Mol Biol. 2018 Mar;58(3):352-365. doi: 10.1165/rcmb.2017-0242OC.
PMID:28960101

A Howling Cause of Pancytopenia.
Casciato A, Lind C, Olson APJ, Binstadt BA, Davis AM.
J Hosp Med. 2018 Mar 1;13(3):205-209. doi: 10.12788/jhm.2855. Epub 2017 Oct 4. No abstract available.
PMID: 29069118

T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells.
Beura LK, Wijeyesinghe S, Thompson EA, Macchietto MG, Rosato PC, Pierson MJ, Schenkel JM, Mitchell JS, Vezys V, Fife BT, Shen S, Masopust D.
Immunity. 2018 Feb 20;48(2):327-338.e5. doi: 10.1016/j.immuni.2018.01.015.
PMID: 29466758

Understanding Subset Diversity in T Cell Memory.
Jameson SC, Masopust D.
Immunity. 2018 Feb 20;48(2):214-226. doi: 10.1016/j.immuni.2018.02.010. Review.
PMID: 29466754

Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory.
Beura LK, Mitchell JS, Thompson EA, Schenkel JM, Mohammed J, Wijeyesinghe S, Fonseca R, Burbach BJ, Hickman HD, Vezys V, Fife BT, Masopust D.
Nat Immunol. 2018 Feb;19(2):173-182. doi: 10.1038/s41590-017-0029-3. Epub 2018 Jan 8.
PMID: 29311694

Strain Tracking Reveals the Determinants of Bacterial Engraftment in the Human Gut Following Fecal Microbiota Transplantation.
Smillie CS, Sauk J, Gevers D, Friedman J, Sung J, Youngster I, Hohmann EL, Staley C, Khoruts A, Sadowsky MJ, Allegretti JR, Smith MB, Xavier RJ, Alm EJ.
Cell Host Microbe. 2018 Feb 14;23(2):229-240.e5. doi: 10.1016/j.chom.2018.01.003.
PMID:29447696

Role of afferent and efferent renal nerves in the development of AngII-salt hypertension in rats.
Foss JD, Fiege J, Shimizu Y, Collister JP, Mayerhofer T, Wood L, Osborn JW.
Physiol Rep. 2018 Feb;6(3). doi: 10.14814/phy2.13602.
PMID:29405658 

Cystic Fibrosis Colorectal Cancer Screening Consensus Recommendations.
Hadjiliadis D, Khoruts A, Zauber AG, Hempstead SE, Maisonneuve P, Lowenfels AB; Cystic Fibrosis Colorectal Cancer Screening Task Force.
Gastroenterology. 2018 Feb;154(3):736-745.e14. doi: 10.1053/j.gastro.2017.12.012. Epub 2017 Dec 29.
PMID:29289528

Cutting Edge: Allograft Rejection Is Associated with Weak T Cell Responses to Many Different Graft Leukocyte-Derived Peptides.
Burrack AL, Malhotra D, Dileepan T, Osum KC, Swanson LA, Fife BT, Jenkins MK.
J Immunol. 2018 Jan 15;200(2):477-482. doi: 10.4049/jimmunol.1701434. Epub 2017 Dec 18.
PMID: 29255075

Cutting Edge: Allograft Rejection Is Associated with Weak T Cell Responses to Many Different Graft Leukocyte-Derived Peptides.
Burrack AL, Malhotra D, Dileepan T, Osum KC, Swanson LA, Fife BT, Jenkins MK.
J Immunol. 2018 Jan 15;200(2):477-482. doi: 10.4049/jimmunol.1701434. Epub 2017 Dec 18.
PMID:29255075

Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma.
Scott MC, Temiz NA, Sarver AE, LaRue RS, Rathe SK, Varshney J, Wolf NK, Moriarity BS, O'Brien TD, Spector LG, Largaespada DA, Modiano JF, Subramanian S, Sarver AL.
Cancer Res. 2018 Jan 15;78(2):326-337. doi: 10.1158/0008-5472.CAN-17-0576. Epub 2017 Oct 24.
PMID: 29066513

MicroRNA-Based Attenuation of Influenza Virus across Susceptible Hosts.
Waring BM, Sjaastad LE, Fiege JK, Fay EJ, Reyes I, Moriarity B, Langlois RA.
J Virol. 2018 Jan 2;92(2). pii: e01741-17. doi: 10.1128/JVI.01741-17. Print 2018 Jan 15.
PMID: 29093096

Memory CD8 T cells mediate severe immunopathology following respiratory syncytial virus infection.
Schmidt ME, Knudson CJ, Hartwig SM, Pewe LL, Meyerholz DK, Langlois RA, Harty JT, Varga SM.
PLoS Pathog. 2018 Jan 2;14(1):e1006810. doi: 10.1371/journal.ppat.1006810. eCollection 2018 Jan.
PMID: 29293660

Do Memory B Cells Form Secondary Germinal Centers? It Depends.
Pape KA, Jenkins MK.
Cold Spring Harb Perspect Biol. 2018 Jan 2;10(1). pii: a029116. doi: 10.1101/cshperspect.a029116. Review.
PMID: 28320756

Functional Genomics of Host-Microbiome Interactions in Humans.
Luca F, Kupfer SS, Knights D, Khoruts A, Blekhman R.
Trends Genet. 2018 Jan;34(1):30-40. doi: 10.1016/j.tig.2017.10.001. Epub 2017 Oct 26. Review.
PMID: 29107345