Tracking the T Cell Repertoire

October 31, 2015

Tracking the T Cell Repertoire...In the December 2015 issue of Nature Reviews Immunology, Dr. Ron Germain describes two seminal papers over the past 25 years from Dr. Marc Jenkins and colleagues that introduced new techniques for the analysis of the T cell repertoire. 

Jenkins Lab papers referenced in the article:

Visualization of peptide-specific T cell immunity and peripheral tolerace induction in vivo.
Kearney ER, Pape KA, Loh DY, Jenkins MK.
Immunity. 1994 Jul;1(4):327-39

Naive CD4+ T Cell Frequency Varies for Different Epitopes and Predicts Repertoire Diversity and Response Magnitude.
Moon JJ, Chu HH, Pepper M, McSorley SJ, Jameson SC, Kedl RM, Jenkins MK.
Immunity. 2007 Aug;27(2):203-13. Epub 2007 Aug 16.