Bruce Walcheck, PhD

Bruce Walcheck

Contact Info

walch003@umn.edu

Office Phone 612-624-2282

Lab Phone 612-624-9741

Mailing Address:
295J AS/VM Building
1988 Fitch Avenue
Saint Paul, MN 55108

Postdoctoral fellow, Boehringer Ingelheim Pharmaceuticals

PhD, Immunology, Montana State University

BS, Microbiology, Montana State University

Summary

Expertise

Leukocyte biology; Flow Cytometry

Research

Research Summary/Interests

Our research is focused on the cell and molecular biology of leukocytes in the context of inflammation and the host response to cancer.

Cell adhesion: leukocyte migration
Our research group is examining various aspects of inflammation regulation. We are interested in the mechanisms that direct leukocytes to sites of inflammation and that regulate their effector activities. A key leukocyte involved in the early inflammatory response is the neutrophil, which is the most abundant leukocyte in the blood and at sites of acute inflammation. Various inflammatory modulators expressed by neutrophils are regulated by a process referred to as ectodomain shedding. Among other lines of research, my lab is actively involved in understanding the function and regulation of this proteolytic process in order to manipulate inflammation and bolster innate immunity or diminish damaging inflammation.

Publications

Teaching

Courses

  • CVM6911 - Veterinary Immunology, Instructor